Tail snip

Please read the general principles of blood sampling page before attempting any blood sampling procedure.

Technique

Snipping the tail surgically is a crude method of sampling and should be avoided as it involves the removal of soft tissue from the tip of the tail using a scalpel, resulting in permanent damage to the tail and pain to the mouse. An additional limitation of the technique includes contamination, with the sample containing tissue fluid as well as blood. The saphenous vein and tail vein are more appropriate routes of sampling for most studies and strains of mice. 

Tail snip technique in other animals

The tail snip technique is not appropriate for use in other species.  

All blood sampling techniques in the mouse

Click here for information on blood vessel cannulation in the mouse Click here for information on tail vessel microsampling in the mouse Click here for information on tail vein blood sampling in the mouse Click here for information on saphenous vein blood sampling in the mouse Click here for information on retro-orbital blood sampling techniques in the mouse Click here for information on abdominal/thoracic blood vessel blood sampling in the mouse Click here for information on cardiac puncture blood sampling in the mouse Click here for information on schedule 1 stunning followed by decapitation in the mouse Click here for information on decapitation blood sampling techniques in the mouse