Glossary

Ambulatory infusion

  • An animal is freely moving without need for a tether to connect with the catheter. This is normally only possible with larger animals that can be fitted with jackets to carry an infusion pump and compound reservoir. Totally implanted pumps can sometimes be used in rodents but have size limitations.

Atraumatic

  • Minimal tissue injury is caused during the procedure.

Bicompatibility

  • Good toleration of implants by animal tissues after implantation.

Biofilm

  • A coating which develops on implanted materials derived from the animal's own tissue fluids and cells.

Catheter

  • Flexible tube inserted into body cavities or organs for medical or experimental procedures.

Dehiscence

  • Bursting open or splitting along natural or sutured lines.

Endothelium

  • The layer of cells lining blood vessels.

Friction coefficient

  • Surface friction influences how easily a catheter can be inserted into a blood vessel and any injury to the vessel lining (endothelium).

Haematogenous spread

  • Spread of microbial infection through the blood stream.

Thrombogenic

  • Property of causing or promoting blood clotting (thrombosis).

Thrombosis

  • The process of blood clotting in which normally fluid blood.

Lumen

  • The cavity within a catheter through which blood is withdrawn or compound infused.

Septum

  • The thick polymer diaphragm allowing sealing a vascular access.

Vascular access port

  • An implantable chamber for intermittent access of catheters by puncture via a self-sealing septum with a special (Huber) needle.

Venepuncture

  • Insertion of a hypodermic needle through skin into a vein to withdraw blood samples or administer compounds.

All resources on vascular catheterisation

Click here for an introduction to implanting catheters in laboratory animals Click here for information on preventing thrombosis when implanting catheters in laboratory animalsClick here for information on the design of catheters for use in laboratory animalsClick here for information on preventing infection when implanting catheters in laboratory animalsClick here for information on planning and designing experiments which will involve implanting catheters into laboratory animals