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Our ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are intended to improve the reporting of research using animals –...
Most animals used in scientific research and testing will be killed at the end of the study. Some animals may die as a direct result of experimental...
The quality of housing and husbandry for laboratory animals has a major impact on their health and welfare. Environments which do not meet the...
Blood sampling can be stressful for laboratory animals because of the handling, restraint, anaesthesia or discomfort associated with a particular...
Practical blood sample volumes for laboratory animals, domestic species and non-human primates are given in the table below (adapted Wolfensohn...
Long-term repeated access to blood vessels for sampling, administering drug compounds and other substances, or measuring blood pressure in laboratory...
Circulating blood has the capacity to clot (form a thrombus) at sites of injury, foreign materials or where blood flow is either slowed or irregular...
The biological, chemical and physical properties which are required for optimal vascular catheter design and construction are listed in detail in...
Catheter-related infection is a major risk factor which can compromise vascular catheter studies.
There are many factors and details that should be addressed to ensure a satisfactory outcome of vascular catheter implantation. It is also necessary...
Ambulatory infusion An animal is freely moving without need for a tether to connect with the catheter. This is normally only possible with larger...
How much blood does a mouse have? On average, mice have around 58.5 ml of blood per kg of bodyweight. A mouse weighing 25 g would therefore have a...
Technique Summary Resources and references Blood vessel cannulation technique in other animals All blood sampling techniques in the mouse Please...
  Information on microsampling (e.g. study designs, sampling protocols, videos) can be found in our microsampling resource. See below for how to...

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