External link
A framework to improve the lives of laboratory rodents through refined management approaches.
83 results
Guidance, information and recommendations for those working with zebrafish.
Recommendations for reducing aggression between group-housed male mice.
Resources and activities around NAMs (replacement technologies used to assess drug and chemical safety).
Join our community of researchers, developers, industry and regulatory end-users working together to accelerate the use of new approach methodologies.
Learn more about what NAMs are and how they can be applied to progress the 3Rs.
Practical advice on calculating how many matings to set up, including available breeding calculator tools.
Guidance on best practices in confirming, archiving and maintaining strains.
A high level introduction to best practice in mouse colony management, including confirming, archiving and maintaining mouse strains.
Answers to some of the most often asked questions on breeding and maintaining GA mouse colonies.
Projects to ensure that the in vivo tests involved in ED assessment are as robust as possible, particularly focusing on aquatic species.
Quarterly e-newsletter to keep the scientific community updated on news from the NC3Rs Toxicology and Regulatory Sciences programme.
Key results and recommendations from an EPAA/MEB/NC3Rs collaboration focused on chronic toxicity studies for monoclonal antibodies (mAbs).
Webinar on the pioneering approach to implementing refinements for handling mice and rats by Research Institutes of Sweden (RISE).
A webinar to highlight available opportunities to minimising non-human primate use in drug development.
Opportunities to reduce the use of non-human primates in toxicology programmes.
A webinar to raise awareness of the microsampling technique and encourage wider adoption.
Archiving can provide a back-up to production colonies, minimise genetic drift, reduce the need for tick-over colonies and preserve valuable models.
A series of workshops as part of our project to implement the 3Rs in WHO guidelines.
Supporting technicians in assessing the welfare impact of enrichment.
Guidance on modifying our example protocols to design your own studies.
Guidance on using motivation tests to evaluate environmental enrichment.
Guidance on using ethograms to evaluate environmental enrichment, including examples.
Guidance on using preference tests to evaluate environmental enrichment.
