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NC3Rs: National Centre for the Replacement Refinement & Reduction of Animals in Research

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Learn more about why the single use of needles should be standard practice and how to implement this in your facility.

A rat being injected with a hypodermic needle
External link

Principles and techniques for humane killing of laboratory animals.

Mice in a cage with a pipe connected to it, to be used for euthanasia.

Posters and other resources on the use of grimace scales to assess pain in laboratory animals.

The mouse, rat and rabbit grimace scale posters layered over each other.

Key issues for the humane killing of laboratory animals.

A laboratory technician and a rat in a tank
External link

Wiki on refinement of the use of chronic implants in neuroscience research using non-human primates.

Chronic Implants Wiki logo

General principles in analgesia to support best practice.

A rabbit not exhibiting any signs of pain

Examples of study designs that may be used for microsampling from either main study animals or from satellite groups of animals.

A lister hooded rat (black head white body) being held by a technician. The technician wears a green gown and purple gloves.