Replacement, Reduction and Refinement
Guidelines, practical information, publications, video and training materials to help you put the 3Rs into practice.
We fund world class researchers to develop predictive, reliable and humane 3Rs approaches.
Details of NC3Rs projects, including grants, early career awards and work led by our staff.
What are the 3Rs? How many animals are used in research? Find answers to these questions and more.
Latest news
Hear from the NC3Rs NAMs Advisory Group as they discuss their recent paper on how to overcome the hurdles to embedding new approach methodologies (NAMs) in chemical and drug safety assessment.
Bringing together oncology researchers to establish collaborations and catalyse the uptake of 3Rs technologies for cancer research.
We have published a report to increase the uptake of non-animal derived antibodies and non-antibody affinity reagents by the research community.
A new paper makes recommendations for dose selection in developmental and reproductive toxicity studies to avoid unnecessary animal suffering, reduce animal use and maintain the highest standards of human health protection.
Working directly with scientists, technicians and research institutions to accelerate the uptake of the 3Rs, our new regional training offering is available free of charge across the UK.
Our Regional Programme Manager, Dr Ellen Forty, speaks to individuals across three UK research establishments about the unique focus the role of a ‘3Rs Champion’ brings to their local research environment.
Discover 3Rs innovations from the NC3Rs
Bringing together expertise from different sectors and disciplines to deliver readily available and easily deployed 3Rs models and tools that are more predictive and cost-effective than current animal models.
