NC3Rs e-newsletter - August 2014


New NC3Rs and CRACK IT websites launched

We have recently launched two new redeveloped websites; the NC3Rs site and the CRACK IT site.

We are continuing to update and add new content to the sites. Please be aware that if you have bookmarked any links to our old site the pages should automatically redirect, however, if you can't find any pages that you are looking for, please contact



2014 Project and Pilot grants awarded

This year we have invested in six new project grants and five new pilot grants. The successful awardees have recently been announced.



Replacing animal models of bovine tuberculosis

With support from the BBSRC, we are inviting applications that aim to develop novel systems that can be used to study TB infection, virulence and host-pathogen interactions, including; in vitro, in silico, tissue engineering, lab-on-a-chip or other appropriate innovative models.

The deadline for outline submission is 11 September 2014, 4pm. For those invited to submit a full application the deadline is 28 October 2014, 4pm.


CRACK IT Challenges launch event

12 September 2014 – LONDON
We are hosting a meeting to launch the competition in central London on 12 September 2014, providing invaluable access to potential new partners and to the Challenge Sponsors. Networking at the event is intended to stimulate discussion between applicants and Sponsors to help put together a winning application.

This event is free to attend but registration is essential. The deadline for registration is 5 September 2014.



Maths and the 3Rs: A science retreat linking biologists and mathematicians

8-12 September 2014 - CAMBRIDGE
The registration deadline for your opportunity to work with leading mathematicians to solve a biological problem with a 3Rs theme is fast approaching. Sign up by 18 August 2014.



Big Brother: Keeping a watchful eye on animal behaviour

10 September 2014 - BIRMINGHAM
We will be at the British Science Festival in September, where three NC3Rs-funded researchers will be showcasing their work that uses the latest video and monitoring technologies to help understand animal behaviour and improve welfare. The event is free to the general public, but registration is advised.



Improving the design, conduct and reporting of in vivo research

5 October 2014 – BUENOS AIRES
If you are attending the World Pain Congress in Buenos Aires, don't forget to register for the satellite meeting organised by the IASP non-human subject special interest group. This event is co- sponsored by the NC3Rs and will be held on Sunday 5 October 2014, a day ahead of the main meeting.


2014 CRACK IT Challenges announced

This year's CRACK IT Challenges have been announced. Three Challeneges have been set, in a range of different areas, including using existing toxicological data repositories to develop in silico tools to predict toxicology endpoints, investigating human safety issues arising from chemicals interacting with 'off-target' receptors, and generating a human stem cell-based model to identify neurotoxicity in vitro.

The launch meeting will be held in central London on 12 September 2014.


The NC3Rs blog is now integrated into our new website.
Find our most recent posts, along with our back catalogue, here.



Saving two birds with one stone…

A recently published study has called into question some aspects of the approach to chemical safety testing required in certain countries and regions suggesting an effective way to evaluate plant protection products whilst using fewer animals.



Embedding the 3Rs in charity-funded research

Dr Martin Turner, Senior Policy Advisor at the Association of Medical Research Charities (AMRC), explains how the AMRC are working together with the NC3Rs to make the 3Rs a priority in charity-funded research.



Hosting an institutional workshop on the 3Rs

The University of Aberdeen recently organised and hosted a large workshop to promote the 3Rs, which included a flagship presentation by the NC3Rs. Iain Grant, Policy Adviser at the university, who was involved in bringing the event together, tells us about his experience of organising the day.



Working together to CRACK dementia

The UnTangle Challenge from CRACK IT brings together great minds from the charity sector, industry and academia to help unravel the mysteries surrounding how the tau protein is linked with the progression of Alzheimer's disease. Dr Eric Karran, Director of Research at Alzheimer's Research UK, tells us why the charity is excited to be involved with the Challenge.





You have received this email because you asked to receive information by email from the NC3Rs.

To unsubscribe please click here.

To ensure our emails are delivered to your inbox and not your junk folder,
please add the email address to your address book or 'safe' list.