NC3Rs e-newsletter - August 2018


2019 Skills and Knowledge Transfer grant scheme: a new partnership with Cancer Research UK


This year marks the beginning of a new collaboration between Cancer Research UK and the NC3Rs as we offer joint awards to support the sharing of 3Rs skills, tools and technologies within cancer research, as part of our wider Skills and Knowledge Transfer grant scheme.



Last chance to register!


We have three exciting events coming up in September and time is running out for you to book your free place.


2019 Funding Highlight Notice Launch Event
4 September, London

2018 CRACK IT Challenges Launch Event
6 September, London

Workshop: Applying the 3Rs in oncology research
24 September, London

Deadline: 28 August

Deadline: 31 August

Deadline: 12 September

Visit our website events page for details of these and other NC3Rs events, as well as events run by other organisations that are relevant to our work.


£2.4m awarded in grants to advance the 3Rs


Refining a mouse model of lung cancer, improving the welfare of zebrafish and reducing the number of frogs needed for research are just three of the projects we have recently funded. This year we have committed a total of £2.4m to seven project grants, funding outstanding 3Rs research in a broad range of disciplines.




New checklists to support the assessment of welfare standards in overseas research


Last year we developed a simple checklist to assist funders in assessing whether rodent research conducted outside of the UK conforms to appropriate welfare standards. We have now released additional checklists for the use of rabbits, sheep, goats and pigs overseas, with more planned for later this year.




Galleria mellonella as a novel non‑mammalian infection model for TB


A pioneering study has shown that a simple invertebrate, larvae of the wax moth Galleria mellonella, can be used as an infection model for tuberculosis. This work, which was partly funded by an NC3Rs PhD Studentship award, demonstrates some of the advantages of non-mammalian models and their potential to replace vertebrates in studies of TB.




Listen to the latest episode of “3 Minute 3Rs”


Take a break and check out the latest episode of the “3 Minute 3Rs” podcast, featuring contributions from Lab Animal, the NA3RsC and the NC3Rs. This month’s papers focus on rat training without water restriction, replacing primary NHP kidney cells in polio vaccine testing, and ageing and frailty indexes for refining rodent models.




New Solution: A human micro‑liver system for reliable safety and efficacy testing


Are you looking for non-animal approaches for assessing liver toxicity? Could you provide advice, compounds or datasets to support the development of a new in vitro technology?


Researchers from the University of Naples are seeking industry partners to further develop and validate their liver‑on‑a‑chip platform, which aims to reduce the number of potential hepatotoxicants entering animal studies.




Training Fellowships scheme 2018: applications closing soon


Our Training Fellowship scheme supports promising early career researchers, focusing on developing new skills and gaining a breadth of research experience. If you have less than three years’ post-doctoral experience, you can apply for two years of funding through the scheme.

The closing date for applications is 4pm on 12 September, so don’t delay.




Primate Welfare Meeting 2018: programme now available


15 November 2018 (Central London)


The programme for this year’s Primate Welfare Meeting is now available online. It features presentations on a range of contemporary topics in non-human primate welfare, flash poster presentations, a keynote lecture and plenty of networking opportunities. Reserve your place now to keep your lab informed about best practice in non-human primate care and use.




How to decide your sample size when the power calculation is not straightforward


Think you don’t need to do a power calculation for your in vivo experiment? Think again! In our latest guest blog post, Dr Simon Bate, Statistics Leader at GSK, addresses some common queries about sample sizes, power calculations and demonstrates how statistics can support the 3Rs.