NC3Rs e-newsletter - August 2019

NC3Rs logo

August 2019

Welcome to the new-look NC3Rs newsletter. We are now using GovDelivery to send our newsletter each month – please ensure that is added to your safe senders list. You can still manage your subscription by logging into the NC3Rs website or unsubscribe via the link at the bottom of every email.

Road test the revised ARRIVE guidelines


The 2019 ARRIVE guidelines and accompanying Explanation and Elaboration document are now available in preprint. We are recruiting volunteers who are preparing a publication containing in vivo research to road test the revised guidelines. As well as improving the quality of your manuscript and helping shape the final development of the guidelines, you will receive a £50/US$60 Amazon voucher to thank you for your time.


If you are interested in taking part, please contact or learn more via our website.


Further information


Revision of the ARRIVE guidelines

New issue of Tech3Rs now out


Our quarterly Tech3Rs newsletter highlights the latest resources, research and events for animal technicians. In the August issue we take a look at the welfare benefits of tickling rats, outline recent publications on using grimace scales to assess pain, and highlight how our Regional Programme Managers can help you advance the 3Rs.


Further information


Tech3Rs August 2019 newsletter

Pre-order our new poster on the single use of needles


In response to the growing interest in avoiding the reuse of needles, we have produced a poster that explains why the single use of needles should be standard practice and provides tips for implementation. You can now pre-order free hard copies for display in your facility via our new reuse of needles hub.


Further information

  Single-use needles

NC3Rs Board Chair recruitment closes soon


We are recruiting a new Chair to lead the NC3Rs Board from January 2020. The new Chair will help shape our strategy and promote the UK as a world leader in 3Rs research. Candidates for this role should have leadership experience and a distinguished international research track record, as well as a vision of priorities and opportunities for the 3Rs across the biosciences.


The deadline to apply is 4pm on Tuesday 27 August.


Further information

  Board Chair recruitment

Share your thoughts on ICH S7


Do you design or perform ICH S7 safety pharmacology studies, or make decisions based on the resulting data? If so, we want to hear from you.


We have teamed up with the Safety Pharmacology Society to produce a survey on the studies outlined within ICH S7 guidance for first-in-human testing of new pharmaceutical products. The survey will take around 10 minutes to complete and will remain open until Friday 30 August.


Further information

  ICH S7 survey

2019 CRACK IT Challenges announced – come to our launch event to learn more

2019 CRACK IT Challenges

The 2019 CRACK IT Challenges are now live. Working with seven Sponsors, we have identified three Challenges to develop new technologies delivering commercial and 3Rs benefits:

£2.5M is available for this year’s competition.


We are launching the 2019 Challenges at an event in central London on Wednesday 11 September. This event will give you invaluable access to potential new partners and to the Challenge Sponsors.


Register via the NC3Rs Innovation Platform before Wednesday 4 September.


Further information

CRACK IT Reception: last few places remaining


Wednesday 11 September (central London)


This evening reception will mark the publication of our 2019 CRACK IT Review, which highlights new 3Rs technologies developed through our CRACK IT programmes. Come along if you want to hear more about CRACK IT from some of the scientists and engineers we’ve funded, as well as how you can get involved.


The deadline to register for this event is Monday 2 September.


Further information

  CRACK IT logo

NC3Rs/IAT Animal Technicians’ Symposium: last chance to register


Wednesday 2 October (central London)


This event, which is aimed primarily at junior technicians, will give you an opportunity to hear about the latest approaches to improving the welfare of laboratory animals and refinement opportunities, as well as network with fellow technicians. Attendees will receive five IAT CPD credits.


Registration for the symposium closes on Friday 13 September – don't miss out on booking your place.


Further information

  2019 NC3Rs/IAT Animal Technicians' Symposium

The NC3Rs at the 70th AALAS National Meeting


Sunday 13-Thursday 17 October 2019 (Denver, Colorado)


At this year’s AALAS National Meeting, we will be delivering talks on improving reproducibility and standardising welfare standards in animal accommodation and care, as well as co-sponsoring a workshop on training monkeys to cooperate with restraint using positive reinforcement techniques for the fourth year running. We will also have a booth (#977) in the trade exhibition, which is taking part in this year’s Technician’s Fun Fair.


Further information

  2019 AALAS Denver logo

Primate Welfare Meeting: poster abstract submission closing soon


Friday 8 November (central London)


This annual event brings together researchers and animal care staff from around the world to share best practice in the use and care of non-human primates. This year’s meeting will have a workshop format and focus on harmonising welfare indicators for macaques and marmosets.


Abstracts for poster presentations should be submitted by 5pm on Friday 30 August.


Further information

  2019 Primate Welfare Meeting

Help us discover more about the secret lives of mice


We have collaborated with MRC Harwell to create Secret Lives of Mice, a new project hosted by Zooniverse that gives anyone the chance to contribute to improving laboratory mouse welfare by watching videos of mice in their home cages and labelling their behaviour. Our latest guest blog post comes from Emma Robinson, a volunteer on the project, who explains why you should get involved.


Further information

  Secret Lives of Mice citizen science project
"3 Minute 3Rs" podcast

NIIMBL grants available for alternative methods in vaccine testing


The US National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL) is offering US$1.5 million in grants to develop and implement innovative technologies for vaccine and biological manufacturing. In vitro assays that reduce the use of animals in lot release testing are particularly encouraged.


The deadline to submit initial concept papers is Tuesday 10 September. This funding opportunity is supported by the NIIMBL Global Health Fund, a collaboration between NIIMBL and the Bill & Melinda Gates Foundation.


Further information

  NIIMBL logo