NC3Rs e-newsletter - February 2019

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Join us in central London on Monday 18 March for the launch of our latest Research Review and the presentation of our annual 3Rs Prize, sponsored by GSK. Don't miss this opportunity to hear about outstanding 3Rs science and technology from NC3Rs-funded scientists and our 2018 prize winner.


The deadline to register is Friday 1 March.




Read the latest issue of our Tech3Rs newsletter


The February edition of Tech3Rs, our newsletter for animal technicians, is now available. This issue focuses on the future of amphibians in research, recent publications on zebrafish welfare, and much more. Read it online or order free hard copies for display in UK facilities.




Announcing four new Training Fellowships


We have awarded Training Fellowships totalling £460k to four talented 3Rs-minded postdoctoral researchers. While working on projects that advance 3Rs approaches, the Fellows will also focus on developing new skills and gaining a breadth of research experience.




2017 Annual Report now online


Our 2017 Annual Report is now available to read online. The report provides an overview of our achievements and impacts throughout the year, from the research we funded to our events, resources and collaborations.




Working together to advance the use of organ-on-a-chip technologies in drug development


We have produced a new report with Medicines Discovery Catapult and the University of Liverpool MRC Centre for Drug Safety Science that outlines recommendations for the advancement of organ-on-a-chip technologies in UK drug development. The report explores how researchers can work together to reduce drug attrition through more human-relevant models.




Join our mouse handling Twitter chat on 5 March


We are hosting a Twitter chat on Tuesday 5 March from 2pm to 4pm (GMT), which will give you a chance to ask questions about refined mouse handling methods and discuss your experiences. Follow along using the hashtag #3Rschat and pose your burning questions to NC3Rs staff members and our guest expert John Waters, a Chief Technician and NACWO at the University of Liverpool.




Last chance to Sponsor a 2019 CRACK IT Challenge


If your organisation is interested in Sponsoring a CRACK IT Challenge this year, the deadline to apply is fast approaching. As a Sponsor, your organisation will identify a scientific Challenge that has the potential to deliver commercial and 3Rs benefits if solved, as well as provide funding or in-kind contributions to support its solution. In return, you will receive early access to the innovative 3Rs technologies that emerge from your Challenge.


The deadline to submit a Challenge is Friday 1 March.




CRACK IT Challenge award to improve monitoring of food intake in group-housed mice


Research Devices Ltd has been awarded £99,382 to develop a new technology for monitoring food intake in group-housed mice, through the 2018 Moshers CRACK IT Challenge. This Challenge is funded by the NC3Rs with in-kind contributions from MRC Harwell, who will provide prototype testing and feedback during the project.




In vitro platform for retinal toxicity assessment and disease modelling


Are you looking for novel 3Rs approaches to assess the safety and efficacy of ocular compounds?


Newcells Biotech Ltd has developed an in vitro model of the retinal pigmented epithelium using human iPS cell lines. An end-user pharmaceutical company is sought to validate the model by providing access to ocular compounds and data with known in vivo and/or in vitro toxicity profiles.




Apply for an NC3Rs public engagement funding award


Are you a past or current NC3Rs grantholder with a great idea for a 3Rs-focused public engagement activity? If so, you could apply for a grant of up to £1,500 to support its development. Apply by Monday 1 April for our next round of funding.




researchfish® submission period now open


If you are the Principal Investigator for an NC3Rs Award, it is time for you to update us on your progress by reporting into researchfish®. This year’s submission period runs until 4pm on Thursday 14 March, so please take this opportunity to share how your 3Rs research is having an impact. Check out our analysis of last year’s researchfish® submissions on our website (PDF).




NC3Rs/Unilever PhD Studentship Launch Event


2 April 2019 (Central London)


This year Unilever will co-fund up to three of our 2019 PhD Studentship awards for projects within safety assessment. If you’re interested in applying for one of these awards, worth £30k per annum over three years, this event will give you the opportunity to find out more. You can also book a one-on-one session to discuss your proposal with a member of NC3Rs or Unilever staff.


Attendance is free, but registration is essential. The closing date for registration is Wednesday 27 March.




The NC3Rs at the 2019 IAT Congress


9-12 April 2019 (North West England)


The Institute of Animal Technology (IAT) Congress is an annual event introducing animal technologists to the latest developments in all aspects of animal-based research and technology. At this year’s event, we will be leading an interactive workshop on the important role animal technologists can play in improving experimental design, with a focus on randomisation and blinding. We will also have a stand in the Congress exhibition hall.


The closing date to register for this year’s Congress is Friday 22 March.