NC3Rs e-newsletter - January 2017


Seven new NC3Rs fellowships announced

We are pleased to announce seven new fellowships: four early career Training Fellowships and three intermediate career David Sainsbury Fellowships, totalling almost £1.2 million.

The awards cover a range of exciting scientific areas from 3D embryonic structures to study left-right asymmetry through to mini-organs for investigating host-pathogen interactions. Further information on our new fellows can be found here.



New PhD studentships announced

Interested in a PhD focusing on 3Rs research and training? There are 11 NC3Rs-funded PhD studentships now available across a broad range of disciplines, including cardiovascular science in a joint award made by the NC3Rs and the British Heart Foundation.



SEARCHBreast helps tissue sharing to benefit the 3Rs

The SEARCHBreast framework, funded by the NC3Rs, enables scientists to share material from animal studies in breast cancer research. The 3Rs and scientific benefits of the framework, and the potential for extending it to other research fields, have recently been highlighted in PLOS Biology.



Out of the box, into the egg: a new way of studying human bone repair in an egg assay

A study, funded by the NC3Rs and published in Scientific Reports, has shown that human bone regeneration can be studied in the extra-embryonic membrane of a developing chick egg, providing a system which could replace some studies in mice, as well as being used to investigate bone loss and injury.



CRACK IT Solution funding: using moth larvae to advance the 3Rs

Funding has been awarded to Biosystems Technology Ltd. through two CRACK IT Solutions grants of £12,000 each, to support research into the potential of TruLarv™ research grade wax moth larvae as an alternative to mammalian tests.

In two separate projects, the University of Exeter spin-out company will partner with contract research organisation Envigo to assess whether the larvae can be used for testing the toxicity of chemicals, and with antibiotic discovery company Demuris for antimicrobial drug screening.



CRACK IT Solutions provider, ZeClinics, awarded €1.8M grant

ZeClinics has been awarded €1.8M of EU funding to support the further development and validation of a prototype technology using zebrafish larvae for assessing cardiotoxicity that was developed as a result of a collaboration funded through the NC3Rs technology partnering hub CRACK IT Solutions.


Find all of our most recent posts, along with our back catalogue here.


The 3Rs potential of human tissue – a funding highlight notice for 2017

In her first blog of the year, NC3Rs Chief Executive Vicky Robinson outlines our new highlight notice, on the use of human tissues for 3Rs purposes, which applies across all of our response mode funding schemes.



Workshop: Human tissue models for cancer research

1 - 2 March 2017: LONDON

We are hosting a two day workshop to discuss how human tissue is used in cancer research. The event programme will focus on engineering the microphysiology of cancer with human tissue, and uses of fresh and fixed human tissue in cancer research.

There will be an opportunity to present posters on relevant work modelling cancer with human tissue. The deadline to submit a poster abstract is 15 February 2017.

Attendance is free, but registration is essential. The closing date for registration is 17 February 2017.



NC3Rs workshop at the Institute of Animal Technology Congress 2017

21 - 24 March 2017: WEST OF ENGLAND, UK

We will be spotlighting the welfare needs of laboratory rodents throughout 2017, running a series of workshops, events and data collection projects aimed at animal technicians.

We will be hosting two workshops in conjunction with AstraZeneca at this year’s IAT Congress, to explore approaches to providing laboratory rats with a complex environment and increased opportunity to exercise.

Each workshop will feature short talks on rat behaviour and welfare as well as group break-out sessions to explore the barriers to adoption of complex rat environments and how to practically implement improvements to the environment of laboratory rats.

The closing date for registration is 3 March 2017.



Systematic reviews in animal research: launch of SyRF

30 March 2017: LONDON

In collaboration with CAMARADES, we will be hosting a meeting to launch the CAMARADES-NC3Rs Systematic Review Facility (SyRF) web app – a new free-to-use tool to help researchers perform systematic reviews and meta-analyses of animal studies.

The meeting is for in vivo researchers who want to learn more about the opportunities systematic reviews present for highlighting 3Rs opportunities, translating animal data to the clinic, and evaluating the risks of experimental bias. It will include a demonstration of the new web app.

Attendance is free, but registration is essential. The closing date for registration is 1 March 2017.