NC3Rs e-newsletter - November 2018


Apply now for the 2018 3Rs Prize


Have you published a paper describing outstanding and original work that has or could have major impacts on the 3Rs? If so, you should apply for our 2018 International 3Rs Prize, sponsored by GSK. This prestigious annual award, worth a total of £30k, recognises a paper published in the last three years with 3Rs impacts.


The deadline for submissions is 4pm (GMT) on Wednesday 5 December 2018.



Tech3Rs newsletter launches


We have launched a new newsletter aimed at animal technicians, focusing on refinements and animal welfare. Tech3Rs will feature updates on the most relevant resources, research and events, supporting technicians to identify opportunities to embed the 3Rs in practice.


Issues will be published quarterly on our website in a downloadable PDF format. Facilities in the UK can also order hard copies for display in your units.




Vacancy: Programme Manager – Research Funding (maternity cover)


Do you have a PhD and post-doctoral experience, as well as experience working in a research funding organisation? We are currently recruiting maternity cover for the position of Research Funding Programme Manager. This role involves working with researchers at all career stages through our Project grant and Skills and Knowledge Transfer grant funding schemes.


The closing date to apply for this vacancy is 29 November 2018.




Discussing the future of amphibians in research


Despite amphibians being widely used in research, knowledge of best practices in their husbandry and welfare remains limited. To help address this, the NC3Rs held a workshop on amphibian welfare in October 2017, in partnership with the Zoological Society of London. A report from this workshop has recently been published in LabAnimal, describing key challenges, potential solutions and the most pressing research questions relating to amphibian welfare.




Use of preferred fluid rewards can reduce fluid restriction in macaque neuroscience experiments


Research funded through an NC3Rs PhD studentship has demonstrated that identifying a laboratory macaque’s preferred choice of fluid can allow fluid restriction to be minimised. The research, carried out at Newcastle University, confirms that using preferred rewards can lead to improvements in the performance of macaques in cognitive tasks while refining fluid restriction protocols.




New UK and China cooperation on reducing laboratory animal use


We have signed a commitment with the China Rural Technology Development Centre to collaborate on promoting scientific and technological innovations in the 3Rs across China. A signing ceremony took place in London in October to mark this milestone in international cooperation, which will see UK and Chinese scientists cooperating to develop 3Rs approaches.




UCL scientists develop welfare-friendly method for training macaques


Researchers at University College London have developed a refined training system for non-human primates that avoids many of the welfare concerns associated with traditional training methods. The tablet-based Mymou system runs continuously in the home cage environment. It employs facial recognition and real-time data analysis to adapt tasks to each individual monkey, offering a technological solution for refining training procedures.




Happy Birthday to the 3 Minute 3Rs podcast!


In November 2017 we teamed up with LabAnimal and the North American 3Rs Collaborative to launch 3 Minute 3Rs, the podcast dedicated to bringing you the latest 3Rs research papers each month. Browse through all our past episodes on SoundCloud or subscribe wherever you listen to podcasts by searching “LabAnimal”.




Support 3Rs science: apply to join our Funding Panels


The deadline to apply for our current Funding Panel vacancies is fast approaching. If you are a senior researcher interested in helping us identify the best 3Rs science to fund, we want to hear from you. Appointments are for three years commencing in January 2019.


We particularly welcome applications from researchers with industry or interdisciplinary experience, as well as applications from currently under-represented groups, including female candidates, ethnic minority candidates and candidates with disabilities.


The deadline for applications is 4pm on 14 November 2018.




Skills and Knowledge Transfer scheme: deadline for informal outline submission


We are now accepting informal outline applications to our Skills and Knowledge Transfer Scheme. This funding scheme supports the transfer of 3Rs approaches between labs and institutions through the sharing of knowledge, skills and expertise to encourage wider uptake. This year’s funding call includes our new joint awards with Cancer Research UK.

Outlines must be submitted to the NC3Rs office by 4pm on 23 November 2018.




Apply for up to £1,500 through our public engagement award scheme


Are you a current or previous NC3Rs grantholder who wants to run a public engagement activity in the new year, perhaps for British Science Week (8-17 March 2019)? We can offer up to £1,500 to fund the development of almost any type of event or activity aimed at engaging the public with the 3Rs.


This funding is available as an open rolling call, with decisions made quarterly. Please submit applications by 1 January 2019 to be considered for the next round of funding.




Workshop: Animal, in vitro and computational models for preclinical analysis of cell-based cancer therapies


19 November 2018 (Central London)


With the Cell and Gene Therapy Catapult, we are hosting a one-day workshop to explore preclinical testing of cell-based therapies for cancer. Topics will include current best practice in developing cell-based therapies, as well as the benefits and limitations of using animal models and alternative in vitro and in silico models. Funding opportunities in preclinical modelling of cell-based therapies will also be highlighted.


Attendance is free, but registration is essential. The closing date for registration is 16 November 2018.




Workshop: Application of non-animal approaches for decision-making in chemical safety assessment


10-11 December 2018 (Central London)


In collaboration with Unilever, we are hosting a two-day workshop exploring how in vitro and in silico approaches can inform safety and efficacy decision-making in product development programmes. Discussions will focus on what is needed to increase confidence in these new approaches.


Attendance is free, but registration is essential. The closing date for registration is 26 November 2018 and the closing date to submit a poster abstract is 16 November 2018.




Newcastle University survey on handling laboratory mice


As part of an NC3Rs award to Dr Johnny Roughan, researchers at Newcastle University are seeking feedback from animal care professionals and researchers on the use of tunnels for picking up laboratory mice, and the possible obstacles or limitations users experience with tunnel handling compared to tail handling.


If you work with laboratory mice, please complete this survey, which will take no more than 15 minutes.