NC3Rs e-newsletter - November 2020

NC3Rs logo

November 2020

Read the latest issue of our Tech3Rs newsletter

If you’re an animal technician, our quarterly Tech3Rs newsletter can help you find ways to put the 3Rs into practice. Our latest issue is now online and features our new resource on colony management, recent papers on non-aversive mouse handling and details of webinar recordings you may have missed.

Read and download Tech3Rs

  Tech3Rs November 2020

Analysing mouse movement in 3D could bring 3Rs benefits to behavioural tests

A recent paper by NC3Rs David Sainsbury Fellow Dr Riccardo Storchi describes a computational approach to automatically track and record the behaviour of freely-moving mice in 3D. This approach is able to describe in detail how mice respond to different sensory stimuli, and could be widely applied in fields reliant on behavioural analysis.

Learn more

  Mapping mouse behaviour in 3D

Refining DNA sampling through skin swabbing in model fish species

Research published in Scientific Reports suggests that skin swabbing provides a less invasive method of DNA collection from small laboratory fish than the commonly used method of fin clipping, while also reducing data variability. This study was funded by an NC3Rs Project grant awarded to Dr William Norton and Professor Iain Barber and could refine and reduce the use of fish in research.

Learn more

  Zebrafish tanks

Protective cap for macaque cranial implants promotes wound healing

A new publication in the Journal of Neuroscience Methods presents a novel device developed to promote wound healing in macaques with cranial implants. Technical and research staff from the University of Oxford and Newcastle University collaborated to develop an easily modifiable head cap to protect the sutured skin margins after surgery.

Learn more

  Rhesus macaque

New e-learning module on post-anaesthetic care (EU21-6)

We have funded a number of e-learning resources that are freely available for training and continuing professional development in laboratory animal care. The latest NC3Rs-funded e-learning module from FLAIRE Learning focuses on recovery from anaesthesia and post-anaesthetic support.

Start the module

  Post-anaesthesic care
3 Minute 3Rs podcast

New product: continual trials apparatus

The continual trials apparatus, developed with NC3Rs PhD Studentship and CRACK IT funding, is a semi-automated technology for studying spontaneous recognition tasks in rats and mice. It allows multiple trials to be run by a single animal in one session with no handling required between trials. This can reduce the number of animals needed by 50%, to a total of eight per experiment, as well as ensuring more reliable and robust data. This easy-to-use device is now available via Campden Instruments Ltd.

Learn more

  Continual trials apparatus

Skills and Knowledge Transfer scheme: applications close soon

The deadline to submit an informal outline for this year’s Skills and Knowledge Transfer scheme is fast approaching. This scheme funds collaborations to transfer 3Rs tools, models and methods between research teams so their 3Rs impacts can be maximised. This year, for the first time, SMEs are also eligible to apply as the lead applicant (either the adopter or the developer of the method), to enable greater connectivity between academia and industry.


The deadline to submit your outline via Je-S is 4pm (GMT) on Friday 27 November. Prospective applicants are encouraged to watch the recording of our webinar from Tuesday 27 October, which provides further information and guidance on the application process.

Learn more

  Skills and Knowledge Transfer award scheme

Apply for this year’s Project grant scheme

The 2021 NC3Rs Project grant scheme is now open for formal outlines via Je-S. The scheme funds the development of new approaches in medical, biological or veterinary research that provide 3Rs benefits and are more predictive, cost-effective and humane than current gold standards.


The closing date for outlines is 4pm (GMT) on Thursday 7 January. If you’re interested in applying, we strongly recommend that you get in touch via to discuss your potential project.

Learn more

  2021 Project grant scheme

Recording: Organ-on-a-chip technology – from a scientific and 3Rs perspective

This webinar from October 2020 showcases some of the organ-on-a-chip research we have funded through our CRACK IT and research funding programmes. Dr Jos Joore (CEO and co-founder, MIMETAS) and Professor Julien Gautrot (Professor in Biomaterials and Biointerfaces, Queen Mary University of London) give insights into their research and highlight the scientific and 3Rs benefits of using organ-on-a-chip technology.

Watch the recording

  Organ-on-a-chip technology

Event: RSB/ASRU Animal Science Meeting

Thursday 10-Friday 11 December (Online)


The Royal Society of Biology Animal Science Group and the Home Office Animals in Science Regulation Unit will co-host the annual Animal Science Meeting over two afternoons. The meeting is aimed at researchers, research support staff, vets, technologists, administrators and AWERB members involved with animal research.


Contact Harriet McAra at or on 020 3925 3445 for further information and apply before Friday 20 November.

Learn more

  Royal Society of Biology logo