NC3Rs e-newsletter - September 2020

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September 2020

Register now for our webinar series celebrating the 3Rs across Europe

Register now for our webinar series celebrating the 3Rs across Europe

Europe is home to a vibrant 3Rs community with a range of organisations who fund or promote science and technology developments that lead to opportunities to replace, reduce and refine the use of animals in research. Many of these developments also lead to the generation of new scientific knowledge that has benefits for human and animal health and the protection of the environment.


To celebrate the 3Rs in Europe, six organisations have come together to organise a virtual event to highlight the latest 3Rs opportunities. The event will be held over three days from 22 to 24 September with presentations from two nominated speakers from each of the organisations. Researchers at all career stages who use animals or are interested in how they can help support the 3Rs are encouraged to participate.

Learn more and register

Join the NC3Rs Board and help shape our strategy

We are seeking up to four new members to join our Board from 1 January 2021. Our Board supports our work by advising us on strategy and monitoring our use of resources and the delivery of our work plan. If you are a senior scientist in academia or industry, or a senior manager or veterinarian in a laboratory animal facility, we would like to hear from you.


The deadline for applications is 4pm on Wednesday 7 October. Interviews will be held on Tuesday 10 November.

Learn more

  Board Chair recruitment

Vacancy: Science Manager – Innovation

We are seeking a Science Manager to join the NC3Rs team and support our CRACK IT Open Innovation Programme. Applicants should have a PhD in a biological science, demonstrable commitment to the 3Rs and the ability to work as part of a dynamic team.


The closing date for applications is Sunday 4 October.

Learn more and apply

  Join the NC3Rs team

Tunnel handling improves the welfare of mice undergoing repeated procedures

New research published in Scientific Reports has shown that the animal welfare benefits of picking up laboratory mice via a tunnel instead of by the tail persist even after repeated restraint, intraperitoneal injection and anaesthesia. The work, led by Dr Lindsay Henderson at Newcastle University, adds to the substantial evidence supporting tunnel handling as a way to reduce handling-related stress, even when experimental protocols require the use of more aversive procedures.

Learn more

  Tunnel handling improves the welfare of mice undergoing repeated procedures

Listen to the 3 Minute 3Rs podcast

Every month, 3 Minute 3Rs provides a recap of the latest 3Rs research papers, chosen by Lab Animal, the North American 3Rs Collaborative and the NC3Rs. Our most recent episode featured papers on ARRIVE 2.0, stress-induced analgesia in zebrafish and an optimised olfactory test. Listen now or subscribe wherever you get your podcasts.

Listen or subscribe now

  3 Minute 3Rs podcast

Apply for this year’s CRACK IT Challenges

CRACK IT Challenges 2020

The 2020 CRACK IT Challenges competition is now open. Up to £3.5 million funding is available to UK and EU-based applicants to solve five Challenges that focus on delivering 3Rs, business and scientific impacts across diverse areas including wound healing, mouse welfare, animal-free reagents and in vitro immunology. This year’s Challenges are supported by 11 Sponsors from across the academic, public, pharmaceutical and fast-moving consumer goods sectors, with co-funding from Dstl, EPSRC and Unilever to support specific Challenges.

Learn more and apply

Latest news from the NC3RsReturning to research: is there an opportunity for you to adopt a 3Rs approach?
  • Do you want to adopt a new in vitroex vivo or in silico model?
  • Is there an approach you could adopt to maximise data using fewer animals?
  • Are you interested in funding to help you adopt or transfer a method to a new collaborator and fully realise the impact of your work?

Apply for an NC3Rs Skills and Knowledge Transfer Award

  • Awards are for up to 24 months
  • Maximum of £75k funding (80% FEC)
  • Apply as either the adopter or the developer of the method
  • Informal outline submission is now open – deadline 4pm on Friday 27 November

Learn more and apply

£2.4 million awarded to support the development of new 3Rs approaches

Our flagship project grant scheme has been running since the NC3Rs' conception in 2004. Following seven new awards, we have now committed over £40m to the development of 3Rs approaches and technologies with lasting 3Rs legacies. This year’s awards include three projects focusing on applying the 3Rs to various aspects of veterinary research.

Learn more

  Colourful test tubes

Register now: 2020 Primate Welfare Meeting

Wednesday 18 November, 3-4.30pm (GMT)

This year’s Primate Welfare Meeting will take place online and will focus on sharing the findings of two international surveys on behavioural management of non-human primates and on welfare indicators for macaques and marmosets. Registration is now open to laboratory personnel working directly with non-human primates.

Learn more and register

  Primate Welfare Meeting 2020

Recording: Compassion fatigue in laboratory animal research

Many laboratory animal technicians enter this profession because they love animals, but this caring role may come at a cost to their own wellbeing. We recently held a joint webinar with the North American 3Rs Collaborative (NA3RsC), presented by NA3RsC Fellow Dr Megan LaFollette, focusing on compassion fatigue and the effect it can have on animal care staff.

Watch the recording

  Compassion fatigue webinar

Recording: The ARRIVE guidelines 2.0

If you are interested in producing reliable and reproducible research, the revised ARRIVE guidelines will help you ensure you report the most critical information. Watch the recording of our ARRIVE 2.0 webinar to find out more about resources to support use of the guidelines and the importance of the “Essential 10” pieces of information.

Watch the recording

  ARRIVE guidelines 2.0

What could an NC3Rs Training Fellowship do for you?

Our Training Fellowship scheme supports promising early career researchers to develop new skills and gain a breadth of research experience, preparing them for an independent career in academia. We recently spoke to Dr Deepali Pal, who has just completed her Training Fellowship, to find out how being an NC3Rs Fellow has helped advance her career.

Read the blog post

  Deepali Pal

Event: Advances in Cell and Tissue Culture Conference (ACTC 2020)

ACTC 2020 will take place over two days on Wednesday 30 September and Thursday 1 October as a virtual event. It will bring together industry and academic researchers working in all areas of in vitro cell culture to exchange knowledge, promote their activities and set up new collaborative projects. Topics covered will include advanced skin and respiratory models, novel models for studying neurological diseases and in vitro models for animal replacement.

Learn more and register

  ACTC 2020