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Working together to advance the use of organ-on-a-chip technologies in drug development

Read our new report, co-produced with Medicines Discovery Catapult and the University of Liverpool MRC Centre for Drug Safety Science.

£1 million awarded for in silico assessment of developmental and reproductive toxicity

This award, made through our CRACK IT Challenges programme, will support the development of a more human-relevant platform for DART testing.

Infographic: marking our 1,000th peer review

Learn more about how our peer review and advice service helps funders and grant applicants to implement the 3Rs as we reach the milestone of 1,000 completed reviews.

CRACK IT 2019: Call for Challenges

Could your organisation sponsor the next CRACK IT Challenge to improve R&D and reduce reliance on animal models?

2018 in review: the top NC3Rs news of the year

From the important role of statistics in implementing the 3Rs to celebrating female researchers, we look back at our most popular news stories and blog posts from the past year.

Seventeen new PhD studentships announced

This year we have funded more PhD studentships than ever before, supporting the 3Rs researchers of the future to establish their careers.

UCL scientists develop welfare-friendly method for training macaques

Use of a touchscreen in their home enclosure leads to high performance levels in macaques without the need for restraint.

Self-organising ‘gastruloids’ mimic early development of mouse embryos

A new 3D cell culture model has the potential to replace the use of mouse embryos in studying early development.

First out of the gate(way): a method for studying Alzheimer’s in vitro

We profile work by Dr Cara Croft and Dr Wendy Noble, whose paper was the first to pass peer review on our F1000Research gateway.

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