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Use the filters below to identify NC3Rs projects relevant to your work by R, topic, model or activity type. If you are looking for something specific, you can add keyword(s) into the search box.

Activity type

Topic

Model

533 results

Improving preclinical proton radiation dosimetry using a biologically relevant murine dosimetry phantom

Principal Investigator: Miss Emma Biglin University of Manchester

Fellowship

Rows of PCR tubes on a yellow background

Embryonic zebrafish models of HACD1-deficiency to replace mammals in congenital myopathy and lipidomic research

Principal Investigator: Dr Gemma Walmsley University of Liverpool

PhD Studentship

High fidelity computational approaches to exploit new structures of cardiac ion channels

Principal Investigator: Dr Andrew Leach University of Manchester

PhD Studentship

Investigation of dopamine transporter dysfunction linked to DAT/SLC6A3 mutations in CRISPR-Cas engineered C. elegans and patient derived iPCSs

Principal Investigator: Dr Eva Kevei University of Reading

PhD Studentship

Modulating Macrophage Phenotypes During Infection In Zebrafish

Principal Investigator: Dr Phillip Elks University of Sheffield

PhD Studentship

Ensuring humane deaths for laboratory birds

Principal Investigator: Dr Jessica Martin University of Edinburgh

PhD Studentship

Developing a stem-cell prostate organoid model - reducing global animal usage in prostate development and cancer studies

Principal Investigator: Dr Adriana Buskin Newcastle University

Fellowship

A stock image of round glass dishes containing blue and green liquid arranged closely together.

Developing gene editing technologies in the non-mammalian infectious disease model organism, Galleria mellonella

Principal Investigator: Mr James Pearce University of Exeter

Fellowship

Characterisation of Galleria mellonella innate immune response to Mycobacterium tuberculosis infection

Principal Investigator: Mr Masanori Asai Imperial College London

Fellowship

An orange Eppendorf rack partly full of PCR tubes.

Refinement of pre-exposure programs to reduce the use of fish in proliferative kidney disease monitoring in aquaculture

Principal Investigator: Dr Hanna Hartikainen University of Nottingham

PhD Studentship

Modelling of thrombus dynamics in a microfluidic 'vasculature'

Principal Investigator: Dr Nicola Mutch University of Aberdeen

PhD Studentship

Portrait of Dr Whyte and Professor Mutch

Drosophila based screening to replace mammalian systems to identify the functional role of candidate genes in controlling muscle dyadic architecture

Principal Investigator: Professor Andrew Trafford University of Manchester

PhD Studentship

Exploring the role of matrix encapsulation on early developmental decisions using non-animal sourced hydrogels

Principal Investigator: Professor Cathy Merry University of Nottingham

PhD Studentship

3D patient-derived organoids: A viable and complementary model to study neural system dysfunction in Alzheimer's Disease

Principal Investigator: Dr Marc Busche University College London

PhD Studentship

Efficacy of artificial imprinted antibodies in driving unwarranted immune responses

Principal Investigator: Dr Shoba Amarnath Newcastle University

PhD Studentship

Human stem cell models of de novo tumorigenesis to replace the use of animals for the study of cancer initiation

Principal Investigator: Dr Cinzia Allegrucci University of Nottingham

PhD Studentship

Defining drug delivery into and across the oral mucosa using a tissue engineering and mathematical modelling approach

Principal Investigator: Professor Craig Murdoch University of Sheffield

Project grant

Reducing and replacing the animal cost of functional genetics in African trypanosomiasis

Principal Investigator: Dr Catarina Gadelha University of Nottingham

Project grant

Preclinical Radiomics: A novel approach linking imaging with biological outcomes in mouse models

Principal Investigator: Dr Kathryn Brown Queen's University Belfast

Fellowship

Validation of an in vitro humanised 3D haematopoietic system to investigate haematological malignancies

Principal Investigator: Professor Helen Wheadon University of Glasgow

Project grant