Improving preclinical proton radiation dosimetry using a biologically relevant murine dosimetry phantom Principal Investigator: Miss Emma Biglin University of Manchester Fellowship
Embryonic zebrafish models of HACD1-deficiency to replace mammals in congenital myopathy and lipidomic research Principal Investigator: Dr Gemma Walmsley University of Liverpool PhD Studentship
High fidelity computational approaches to exploit new structures of cardiac ion channels Principal Investigator: Dr Andrew Leach University of Manchester PhD Studentship
Investigation of dopamine transporter dysfunction linked to DAT/SLC6A3 mutations in CRISPR-Cas engineered C. elegans and patient derived iPCSs Principal Investigator: Dr Eva Kevei University of Reading PhD Studentship
Modulating Macrophage Phenotypes During Infection In Zebrafish Principal Investigator: Dr Phillip Elks University of Sheffield PhD Studentship
Ensuring humane deaths for laboratory birds Principal Investigator: Dr Jessica Martin University of Edinburgh PhD Studentship
Developing a stem-cell prostate organoid model - reducing global animal usage in prostate development and cancer studies Principal Investigator: Dr Adriana Buskin Newcastle University Fellowship
Developing gene editing technologies in the non-mammalian infectious disease model organism, Galleria mellonella Principal Investigator: Mr James Pearce University of Exeter Fellowship
Characterisation of Galleria mellonella innate immune response to Mycobacterium tuberculosis infection Principal Investigator: Mr Masanori Asai Imperial College London Fellowship
Refinement of pre-exposure programs to reduce the use of fish in proliferative kidney disease monitoring in aquaculture Principal Investigator: Dr Hanna Hartikainen University of Nottingham PhD Studentship
Modelling of thrombus dynamics in a microfluidic 'vasculature' Principal Investigator: Dr Nicola Mutch University of Aberdeen PhD Studentship
Drosophila based screening to replace mammalian systems to identify the functional role of candidate genes in controlling muscle dyadic architecture Principal Investigator: Professor Andrew Trafford University of Manchester PhD Studentship
Exploring the role of matrix encapsulation on early developmental decisions using non-animal sourced hydrogels Principal Investigator: Professor Cathy Merry University of Nottingham PhD Studentship
3D patient-derived organoids: A viable and complementary model to study neural system dysfunction in Alzheimer's Disease Principal Investigator: Dr Marc Busche University College London PhD Studentship
Efficacy of artificial imprinted antibodies in driving unwarranted immune responses Principal Investigator: Dr Shoba Amarnath Newcastle University PhD Studentship
Human stem cell models of de novo tumorigenesis to replace the use of animals for the study of cancer initiation Principal Investigator: Dr Cinzia Allegrucci University of Nottingham PhD Studentship
Defining drug delivery into and across the oral mucosa using a tissue engineering and mathematical modelling approach Principal Investigator: Professor Craig Murdoch University of Sheffield Project grant
Reducing and replacing the animal cost of functional genetics in African trypanosomiasis Principal Investigator: Dr Catarina Gadelha University of Nottingham Project grant
Preclinical Radiomics: A novel approach linking imaging with biological outcomes in mouse models Principal Investigator: Dr Kathryn Brown Queen's University Belfast Fellowship
Validation of an in vitro humanised 3D haematopoietic system to investigate haematological malignancies Principal Investigator: Professor Helen Wheadon University of Glasgow Project grant