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The Drosophila adult intestine as a model for radiation tolerance and resistance

Principal Investigator: 

  • Dr Joaquin de Navascues

Institution: 

  • Cardiff University
  • Pilot study grant

Determining the source of variability within experimental stroke models

Principal Investigator: 

  • Dr Claire Gibson

Institution: 

  • University of Leicester
  • Pilot study grant

Refining the mouse model of footpad immunisation and infection

Principal Investigator: 

  • Dr Owain Millington

Institution: 

  • University of Strathclyde
  • Pilot study grant

Development of human ex vivo bone-tumour niche for the study of cancer bone disease

Principal Investigator: 

  • Dr James Edwards

Institution: 

  • University of Oxford
  • Pilot study grant

EFucci an atlas of proliferation to reduce mouse usage in embryonic proliferation assays

Principal Investigator: 

  • Dr Richard Mort

Institution: 

  • MRC Human Genetics Unit
  • University of Edinburgh
  • Pilot study grant

Investigation of behavioural and physiological responses to fin-clipping in zebrafish

Principal Investigator: 

  • Ms Gidona Goodman

Institution: 

  • University of Edinburgh
  • Pilot study grant

The use of gene expression profiles to predict protective immunity without the need for disease challenge

Principal Investigator: 

  • Dr Roland Ashford

Institution: 

  • Veterinary Laboratories Agency
  • Pilot study grant

CRANNME: The complete removal of animal use for neuromuscular effectors testing

Principal Investigator: 

  • Professor Mark Lewis

Institution: 

  • Loughborough University
  • Pilot study grant

Live real-time imaging of life-threatening invasive fungal infections

Principal Investigator: 

  • Dr Donna MacCallum

Institution: 

  • University of Aberdeen
  • Pilot study grant

Non-invasive imaging to reduce and refine the use of animals and monitor their welfare during the course of experimentations in oncology

Principal Investigator: 

  • Dr Francois Lassailly

Institution: 

  • Cancer Research UK
  • Pilot study grant

A fully-automated system for positive reinforcement training of group-housed non-human primates

Principal Investigator: 

  • Dr Andrew Jackson

Institution: 

  • Newcastle University
  • Pilot study grant

Pilot study investigating the use human stem cell derived neurons in toxicity testing

Principal Investigator: 

  • Dr Eric Hill

Institution: 

  • Aston University
  • Pilot study grant

Feasibility of replacing invasive heart pressure measurements with non-invasive MR Elastography to reduce rodent numbers in pre-clinical research

Principal Investigator: 

  • Dr Jurgen Schneider

Institution: 

  • University of Oxford
  • Pilot study grant

Individually customisable, non-invasive head immobilisation for primates with the option for voluntary engagement

Principal Investigator: 

  • Professor Christopher Petkov

Institution: 

  • Newcastle University
  • Pilot study grant

Optimising liver equivalents to model liver fibrosis

Principal Investigator: 

  • Dr Fiona Oakley

Institution: 

  • Newcastle University
  • Pilot study grant

Using C. elegans to produce proteins from parasitic nematodes for research and therapeutic use

Principal Investigator: 

  • Dr David Weinkove

Institution: 

  • Durham University
  • Pilot study grant

Reducing the number of non-human primates in research by developing a rodent model of selective attention

Principal Investigator: 

  • Dr Samuel Solomon

Institution: 

  • University College London
  • Pilot study grant

Establishment of non-transformed, continuously growing, alternatively activated mouse macrophage cell lines

Principal Investigator: 

  • Dr Gyorgy Fejer

Institution: 

  • University of Southampton
  • Pilot study grant

Development of an in vitro screening system to minimise animal use in the search for factors that modulate (re)myelination

Institution: 

  • University of Glasgow
  • Pilot study grant

Towards an in vitro system of predictive biomarkers of in vivo liposome efficacy

Principal Investigator: 

  • Dr Andrew Devitt

Institution: 

  • Aston University
  • Pilot study grant

Novel approaches to immortalise salmon fish cells

Principal Investigator: 

  • Dr Bertrand Collet

Institution: 

  • Marine Scotland Science
  • Pilot study grant

Attention Bias: A novel method to assess psychological well-being in group-housed non-human primates.

Principal Investigator: 

  • Dr Emily Bethell

Institution: 

  • Liverpool John Moores University
  • Pilot study grant

Finding effective analgesics in zebrafish by analysing effects on the nervous system (CNS)

Principal Investigator: 

  • Professor Catherina Becker

Institution: 

  • University of Edinburgh
  • Pilot study grant

Investigating tuberculosis by engineering human granulomas

Principal Investigator: 

  • Dr Liku Tezera

Institution: 

  • University of Southampton
  • Pilot study grant