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Development of an AOP for cardiotoxicity mediated by the blockade of L-type calcium channel

Strategic grant

Brunel University

Opportunities to apply the 3Rs in the safety assessment of nanomaterials

Office-led project

Adoption of the Fixed Concentration Procedure for acute inhalation studies

Office-led project

Applying pathways-based approaches across the biosciences

Office-led project

Imprecision and importance: Probabilistic graphical models in toxicology

Strategic grant

University of York

Structural identifiability and indistinguishability analysis as tools for quantitative and systems pharmacology to support the 3Rs

Strategic grant

University of Warwick

Uncertainty and confidence in applying mathematical models and in vitro data in toxicological safety assessments

Strategic grant

University of Leeds