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Transgene Track - An imaging approach to track AAV gene therapies and CAR T-cells in vivo

  • CRACK IT Challenge

RaTS - Developing a device for objective monitoring of rheumatoid arthritis progression in rodents

  • CRACK IT Challenge

Generation of functionally mature pancreatic organoids as a replacement strategy for animal-models of pancreatitis and pancreatic cancer

Institution: 

  • King's College London
  • Fellowship

Understanding brain regeneration in a zebrafish larval model of intracerebral haemorrhage

Institution: 

  • University of Manchester
  • Fellowship

Preclinical Radiomics: A novel approach linking imaging with biological outcomes in mouse models

Institution: 

  • Queen's University Belfast
  • Fellowship

Optimisation and validation of 3D models of progressive human lung fibrosis

Principal Investigator: 

  • Mr Joseph Bell

Institution: 

  • University of Southampton
  • Fellowship

Supporting the adoption of microphysiological systems for COVID research

  • Office-led project

Replacement of animal use in measuring cardiomyocyte response to drug safety profiling using a novel NMR metabolomics technology

Institution: 

  • University of Liverpool
  • PhD Studentship

Investigating biomechanical responses in healthy and diseases ageing cartilage - a tissue engineering approach

Institution: 

  • Newcastle University
  • PhD Studentship

Targeted protein degradation as a novel approach to study protein function in human platelets

Institution: 

  • University of Bristol
  • PhD Studentship

A novel in vitro reporter system for blood stem cell activity

Institution: 

  • University of York
  • PhD Studentship

Refining the tagging of wild fish and sharks

Institution: 

  • University of Exeter
  • PhD Studentship

Understanding how altered brain metabolism causes mitochondrial disease

Institution: 

  • King's College London
  • PhD Studentship

Combining a fully synthetic hydrogel with human intestinal organoids to model pathological matrix remodelling in Inflammatory Bowel Disease

Institution: 

  • King's College London
  • PhD Studentship

A novel Drosophila model of chronic inflammatory lung disease to explore airway damage, inflammation and infection in vivo

Institution: 

  • University of Bristol
  • PhD Studentship

3D bioprinted microtissues to develop patient-specific non-animal technologies (NAT) in cancer drug development

Institution: 

  • Northumbria University
  • PhD Studentship

Insects as models to study wound healing, infection and the wound microbiome

Institution: 

  • Brunel University
  • PhD Studentship

A 3Rs approach to investigate the feto-maternal interface: visualisation of pathogen and antibody in a 3D in vitro human placental model

Institution: 

  • University of Liverpool
  • PhD Studentship

Development and validation of 3D in vitro dormant myeloma cell models to reduce and replace animal studies

Institution: 

  • University of Sheffield
  • PhD Studentship

Drug risk assessment and repurposing using biomimetic chromatography and body-on-chip technology

Institution: 

  • University of Edinburgh
  • PhD Studentship

Breeding and colony management

  • Office-led project

Review of animal use requirements in WHO biologics guidelines

  • Office-led project

Preneoplastic Pancreatic (PanIN) Organoids as an in vitro Model of Pancreatic Cancer Progression

Institution: 

  • University of Liverpool
  • Project grant

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