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Development of in vitro human and rat proximal tubule cell models as a platform for drug transporter and drug-drug interaction studies

Principal Investigator: 

  • Dr Colin Brown

Institution: 

  • Newcastle University
  • PhD Studentship

Spontaneous recognition tasks and the 3Rs

Principal Investigator: 

  • Dr Alexander Easton

Institution: 

  • Durham University
  • PhD Studentship

Zebrafish behavioural assays to identify genetic mechanisms underlying drug seeking and addiction

Principal Investigator: 

  • Dr Caroline Brennan

Institution: 

  • Queen Mary University of London
  • Project grant

Highly differentiated cultures of ferret airway epithelium for the study of respiratory viruses, including influenza

Principal Investigator: 

  • Professor Wendy Barclay

Institution: 

  • Imperial College London
  • Project grant

The human tumour micro-environment modelled in in vitro biomatrices and applied to cancer drug discovery

Principal Investigator: 

  • Dr Anna Grabowska

Institution: 

  • University of Nottingham
  • Project grant

Assessing the welfare of mice used in cancer research

Principal Investigator: 

  • Dr John Roughan

Institution: 

  • Newcastle University
  • Project grant

An in vitro model for pain and neurogenic inflammation in the oro-facial region and upper airways

Principal Investigator: 

  • Dr Fionnuala Lundy

Institution: 

  • Queen's University Belfast
  • PhD Studentship

Using non-invasive in vivo imaging to address the 3Rs in high-throughput mouse phenotyping

Principal Investigator: 

  • Dr Mark Lythgoe

Institution: 

  • University College London
  • PhD Studentship

Refining, reducing and replacing in vivo WHO-standard preclinical assays of snake venom pathology and antivenom efficacy

Principal Investigator: 

  • Dr Robert Harrison

Institution: 

  • Liverpool School of Tropical Medicine
  • PhD Studentship

Reducing animal dependency in diabetes research through pancreatic stem cells

Principal Investigator: 

  • Professor Mark Dunne

Institution: 

  • University of Manchester
  • PhD Studentship

Non-human primate welfare meeting

  • Office-led project

Refining food and fluid control in behavioural neuroscience with macaques

  • Office-led project

Training using positive reinforcement

  • Office-led project

Weaning of macaques

  • Office-led project

Characterisation and validation of an organotypic slice culture model of Alzheimer’s disease

Institution: 

  • King's College London
  • PhD Studentship

Development of a non-animal model for characterizing drug-resistant tumours

Principal Investigator: 

  • Professor Catherine Pears

Institution: 

  • University of Oxford
  • PhD Studentship

A Drosophila model of Candida albicans gastrointestinal infection

Principal Investigator: 

  • Professor Petros Ligoxygakis

Institution: 

  • University of Oxford
  • PhD Studentship

The use of honeybees to screen for toxins

Principal Investigator: 

  • Dr Helen M Thompson

Institution: 

  • Food and Environment Research Agency
  • Project grant

DM-MAP: drug and metabolite microsampling analytical platform for preclinical medicines development

Principal Investigator: 

  • Dr Darragh Murnane

Institution: 

  • University of Hertfordshire
  • PhD Studentship

Development of a non-mammalian, pre-clinical screening tool (FETOX) for predictive analysis of drug safety

Principal Investigator: 

  • Dr Grant Wheeler

Institution: 

  • University of East Anglia
  • PhD Studentship

Development of a refined model of neuropathic pain: a model without frank nerve injury

Principal Investigator: 

  • Dr Andrew Dilley

Institution: 

  • University of Sussex
  • PhD Studentship

Find the target of valproic acid: pioneering the use of a non-animal model for basic biomedical (epilepsy) research

Principal Investigator: 

  • Professor Robin Williams

Institution: 

  • Royal Holloway University of London
  • PhD Studentship

Development of a method for non-lethal sampling from individual fish to investigate host responses to ectoparasites

Principal Investigator: 

  • Professor Chris Secombes

Institution: 

  • University of Aberdeen
  • PhD Studentship

Developing microfluidic systems for high throughput studies of functional neuronal networks

Principal Investigator: 

  • Dr Michele Zagnoni

Institution: 

  • University of Strathclyde
  • PhD Studentship

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