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Reducing and replacing the animal cost of functional genetics in African trypanosomiasis

Institution: 

  • University of Nottingham
  • Project grant

Live monitoring of foreign-body response in animals by diffuse Raman spectroscopy

Institution: 

  • University of Nottingham
  • Project grant

Transgene Track - An imaging approach to track AAV gene therapies and CAR T-cells in vivo

  • CRACK IT Challenge

RaTS - Developing a device for objective monitoring of rheumatoid arthritis progression in rodents

  • CRACK IT Challenge

Understanding brain regeneration in a zebrafish larval model of intracerebral haemorrhage

Institution: 

  • University of Manchester
  • Fellowship

Targeted protein degradation as a novel approach to study protein function in human platelets

Institution: 

  • University of Bristol
  • PhD Studentship

A novel in vitro reporter system for blood stem cell activity

Institution: 

  • University of York
  • PhD Studentship

A 3Rs approach to investigate the feto-maternal interface: visualisation of pathogen and antibody in a 3D in vitro human placental model

Institution: 

  • University of Liverpool
  • PhD Studentship

Development and validation of 3D in vitro dormant myeloma cell models to reduce and replace animal studies

Institution: 

  • University of Sheffield
  • PhD Studentship

Breeding and colony management

  • Office-led project

Cryo-storing research lines of chicken to eliminate breeding and save genetic resources

Institution: 

  • University of Edinburgh
  • Project grant

Using a novel, high welfare in vivo feeding device for poultry red mite and its integration with other novel tools for this parasite

Institution: 

  • Moredun Research Institute
  • Skills and Knowledge Transfer grant

Sharing new non-invasive circadian phenotyping methods

Institution: 

  • University of Oxford
  • Skills and Knowledge Transfer grant

Naturally sterile hybrid mice for the production of embryo transfer recipients

Institution: 

  • University of Oxford
  • Skills and Knowledge Transfer grant

MacuSIM: A microfluidic, in vitro model of the outer retina as an experimental platform for macular disease and therapeutic trials

Institution: 

  • University of Southampton
  • Fellowship

A novel embryonic zebrafish model to replace mammals in the study of 3-hydroxyacyl CoA dehydratase 1-associated muscle disorders

Institution: 

  • University of Liverpool
  • Fellowship

Modelling radiobiology effects of X-rays in small laboratory animals to develop guidelines for preclinical computed tomography imaging

Institution: 

  • University of Edinburgh
  • Fellowship

A computational framework to investigate the mechanical role of the extracellular matrix in tissue development and disease

Institution: 

  • University College London
  • Fellowship

Development of non-mammalian, preclinical screening tools for the predictive analysis of cardiotoxicity

Institution: 

  • University of East Anglia
  • PhD Studentship

Developing an in silico, spectroscopic imaging toolkit for assessing skin penetration

Institution: 

  • University of Surrey
  • PhD Studentship

A 3Rs approach to assess drug toxicity on the mammalian embryo during early pregnancy in vitro

Institution: 

  • University of Liverpool
  • PhD Studentship

Direct replacement of secondary antibodies by Affimer proteins

Institution: 

  • University of Leeds
  • PhD Studentship

A next generation Quiescence and Cell Cycle Indicator for the refinement and reduction of animal usage in proliferation assays

Institution: 

  • Lancaster University
  • PhD Studentship

3D bio-printing human pluripotent stem cell-derived skeletal muscle constructs for disease modelling and drug discovery

Institution: 

  • Queen Mary University of London
  • PhD Studentship

A novel tool that embeds 3Rs principles in multiple sclerosis research

Institution: 

  • University of Glasgow
  • PhD Studentship

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