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The Drosophila adult intestine as a model for radiation tolerance and resistance

Principal Investigator: 

  • Dr Joaquin de Navascues

Institution: 

  • Cardiff University
  • Pilot study grant

Development of human ex vivo bone-tumour niche for the study of cancer bone disease

Principal Investigator: 

  • Dr James Edwards

Institution: 

  • University of Oxford
  • Pilot study grant

Generating zebrafish models of human eye movement disorders to replace mouse models

Principal Investigator: 

  • Dr Ivana Poparic

Institution: 

  • King's College London
  • Fellowship

Molecularly Imprinted Nanoparticles (MIP NPs) as non-animal antibodies substitutes for detection of viruses

Principal Investigator: 

  • Dr Alessandro Poma

Institution: 

  • University College London
  • Fellowship

Contribution of autophagy to the maintenance, invasion and metastasis of melanoma stem-like sub populations.

Institution: 

  • Newcastle University
  • Fellowship

Labelled IMS TAG Proteins for Quantitative Mass Spectrometry Imaging

Principal Investigator: 

  • Professor Malcolm Clench

Institution: 

  • Sheffield Hallam University
  • Strategic grant

iPS cells from ALS patients: Towards replacing animal models for ALS

Principal Investigator: 

  • Dr Vasanta Subramanian

Institution: 

  • University of Bath
  • Project grant

A compartmentalised chamber for the in vitro study and manipulation of axon degeneration

Principal Investigator: 

  • Professor Victor H Perry

Institution: 

  • University of Southampton
  • Project grant

Drosophila as a model for Alzheimer's disease

Principal Investigator: 

  • Dr Kevin Moffat

Institution: 

  • University of Warwick
  • Project grant

Development and validation of in vitro methods for assaying cancer stem cell responses to therapeutic challenge

Principal Investigator: 

  • Professor Ian MacKenzie

Institution: 

  • Queen Mary University of London
  • Project grant

Engineering fully functional, integrated skeletal muscle

Principal Investigator: 

  • Professor Mark Lewis

Institution: 

  • Loughborough University
  • Project grant

Establishment and validation of a stable, cell-based diabetic wound bioassay

Principal Investigator: 

  • Professor Phil Stephens

Institution: 

  • Cardiff University
  • Project grant

Development of a mechanistically informative genome-wide, replacement chemicals screening technology

Principal Investigator: 

  • Professor Andrew Cossins

Institution: 

  • University of Liverpool
  • Project grant

A tissue engineering approach to reduce animal use in renal development and renal organ replacement technology

Principal Investigator: 

  • Professor Jamie Davies

Institution: 

  • University of Edinburgh
  • Project grant

Modelling the human asthmatic airway by tissue engineering

Principal Investigator: 

  • Professor Donna Davies

Institution: 

  • University of Southampton
  • Project grant

Development of a new human cell genotoxicity assay to reduce the use of live animals in drug development

Principal Investigator: 

  • Professor Richard Walmsley

Institution: 

  • University of Manchester
  • Project grant

Pseudoislets as a model system to study beta cell dysfunction in diabetes

Principal Investigator: 

  • Professor Peter Jones

Institution: 

  • King's College London
  • Project grant

An in vitro model of the human alveolus to predict the efficacy of systemic antifungal therapy

Principal Investigator: 

  • Professor William Hope

Institution: 

  • University of Manchester
  • Project grant

In vitro multi-chamber systems for studying neural degeneration processes

Principal Investigator: 

  • Professor Victor H Perry

Institution: 

  • University of Southampton
  • Project grant

Development of an in vitro model for the anterior region of the eye

Principal Investigator: 

  • Dr Nigel Fullwood

Institution: 

  • Lancaster University
  • Project grant

Cell lines for prediction of drug metabolism and toxicity in man

Principal Investigator: 

  • Professor Charles Wolf

Institution: 

  • Dundee Technopol CXR Biosciences Ltd
  • Project grant

Replacement of the mouse bioassay: Development of SPE and LC-MS for detection of paralytic shellfish poisoning toxins

Principal Investigator: 

  • Dr Elizabeth A Turrell

Institution: 

  • Marine Scotland Science
  • Project grant

The development of a cell-based diabetic wound bioassay

Principal Investigator: 

  • Professor David Thomas

Institution: 

  • Cardiff University
  • Project grant

Developing molecular therapies for glaucoma using an ex vivo human organ culture system

Principal Investigator: 

  • Professor Colin Willoughby

Institution: 

  • University of Liverpool
  • PhD Studentship

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