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Development and validation of a rodent touchscreen battery for assessing motivation and affective state

Institution: 

  • University of Cambridge
  • Project grant

Modelling liver fibrosis using human Induced Pluripotent Stem Cells

Institution: 

  • University of Cambridge
  • Project grant

Development of a tetanus-sensitive cell line for assaying tetanus toxin activity

Institution: 

  • University of Sheffield
  • Project grant

A multi-cellular 3D model of human breast tissue to replace rodent xenograft models in breast cancer research

Institution: 

  • University of Nottingham
  • Project grant

Reducing animal numbers in tasks of memory

  • CRACK IT Solution

Advancing the development and application of non-animal technologies (NATs)

  • Office-led project

Replacing, reducing and refining the use of animals in anti-filarial drug testing

Principal Investigator: 

  • Dr Joseph Turner

Institution: 

  • Liverpool School of Tropical Medicine
  • PhD Studentship

Developing tools for functional assessment of a milder model of stroke

Principal Investigator: 

  • Dr Rebecca Trueman

Institution: 

  • University of Nottingham
  • PhD Studentship

Development of a 3D mouse atlas tool for improved non-invasive imaging of orthotopic mouse models of pancreatic cancer

Principal Investigator: 

  • Dr Jane Sosabowski

Institution: 

  • Queen Mary University of London
  • PhD Studentship

Using proxy measures of a depressive-like state to assess the impact of pre-clinical models of chronic diseases on the welfare of mice

Principal Investigator: 

  • Dr Tom Smulders

Institution: 

  • Newcastle University
  • PhD Studentship

A non-mammalian model for neurofunctional studies of vertebrate dopamine signalling

Principal Investigator: 

  • Dr Jonathan McDearmid

Institution: 

  • University of Leicester
  • PhD Studentship

An organotypic model of bronchial dysplasia

Institution: 

  • University of Cambridge
  • PhD Studentship

Improving the welfare and monitoring of rodents undergoing experimental stroke studies

Principal Investigator: 

  • Dr Claire Gibson

Institution: 

  • University of Leicester
  • PhD Studentship

C. elegans model to unravel the role of Klotho in ion metabolism and ageing

Principal Investigator: 

  • Dr Tarja Kinnunen

Institution: 

  • University of Huddersfield
  • PhD Studentship

An ovarian cancer model on a chip

Principal Investigator: 

  • Dr Julien Gautrot

Institution: 

  • Queen Mary University of London
  • PhD Studentship

Enhancing mouse whole embryo culture for use in birth defects research

Principal Investigator: 

  • Professor Andrew Copp

Institution: 

  • University College London
  • PhD Studentship

A non-mammalian model to study innate immune modulation of airways remodelling in asthma

Institution: 

  • University of Sheffield
  • Strategic grant

Developing a non-animal model system to investigate bitter tastants as new treatments for asthma

Principal Investigator: 

  • Professor Robin Williams

Institution: 

  • Royal Holloway University of London
  • Strategic grant

Developing a model for the study of respiratory inflammation in the zebrafish

Principal Investigator: 

  • Professor Margaret Dallman

Institution: 

  • Imperial College London
  • Strategic grant

Use of Drosophila models to explore the function of asthma susceptibility genes

Principal Investigator: 

  • Professor Donna Davies

Institution: 

  • University of Southampton
  • Strategic grant

Applying mathematics to 3Rs problems

  • Office-led project

Use of microsampling to reduce and refine animal use

  • Office-led project

Humane endpoints for rodenticide testing

Principal Investigator: 

  • Dr Alan MacNicoll

Institution: 

  • Department for Environment
  • Food & Rural Affairs (Defra)
  • Project grant

Engineering tissue alternatives to animals

  • Office-led project

Reducing animal use in complex systems: using nausea and vomiting as a test case

  • Office-led project

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