New CRACK IT Solution funding: using moth larvae to advance the 3Rs
Scientists at BioSystems Technology receive partnership funding to explore use of moth larvae for antimicrobial drug screening.
Video tutorial: practical advice on mouse handling
Learn how to handle mice with minimal stress for the animals.
Animal Technicians' Symposium presentations
Watch the presentations from the 2016 joint NC3Rs/IAT Animal Technicians’ Symposium.
New SEARCH framework for the sharing of animal tissue
NC3Rs-funded SEARCHBreast initiative aims to make the resource more accessible to the scientific community.
The 3Rs potential of human tissue in research
Our Chief Executive has announced a funding highlight notice in her latest blog.
CRACK IT Solutions funding increases to £50k
Do you have technology with 3Rs potential? Apply to our Solutions partnering hub.
Survey on the use of zebrafish in research highlights opportunities for refinement
We co-conducted an international survey to help laboratories to benchmark their husbandry practices and improve fish welfare.
Using fewer animals to assess environmental safety
Approaches available to minimise the use of vertebrates in evaluating chemical safety.
Seven new fellowships funded by the NC3Rs
Leading in the development of novel approaches to advance the 3Rs.
New PhD studentships available to promote the 3Rs in training
11 PhD studentships have been awarded, totalling nearly £1 million in funding.
Paper shows a new way of studying human bone repair
Human bone regeneration can now be studied in developing chick egg membrane.
What are the 3Rs?
The principles of the 3Rs (Replacement, Reduction and Refinement) were developed as a framework for humane animal research.

The NC3Rs

If you are a scientist, animal technician, veterinarian, regulator, funder or policy maker, the NC3Rs can you help to:

  • Drive scientific and technological developments that replace, reduce or refine the use of animals in research (the 3Rs)
  • Ensure your animal experiments are as robust and reproducible as possible
  • Provide the best welfare for laboratory animals


Science-led and evidence-based, we fund research and early careers, foster collaborations between universities and industry to develop and commercialise 3Rs technologies, and provide information on the latest advances to put the 3Rs into practice.

Keep in touch

Open calls

Submission date:
We are now inviting the submission of informal outlines to the 2017 call.