International 3Rs prize - deadline soon
A £30k prize for the best publication which positively impacts upon the 3Rs.
New studies show impact of the ARRIVE guidelines
Studies show the role of ARRIVE guidelines in reducing bias during experimentation.
Animal Technicians' Symposium presentations
Watch the presentations from the 2016 joint NC3Rs/IAT Animal Technicians’ Symposium.
The Experimental Design Assistant
Use the EDA to help guide you to design experiments whilst using the minimum number of animals consistent with scientific objectives.
Video tutorial: mouse handling made easier
Our resource focuses on best practice in the handling of laboratory mice.
New e-learning resource on laboratory animal euthanasia
Resource to help train research workers in the humane killing of laboratory animals.
Order pocket-sized ARRIVE Guidelines
Receive free copies of our guidelines, designed to improve the reporting of research using animals
Resources from the NC3Rs
We provide an extensive library of 3Rs resources including guidelines, practical information and themed hubs.
BLOG: What's it like to be an NC3Rs Panel member?
Professor Lucy Walker sheds more light on what it is like to be part of an NC3Rs Panel.
A new model of mammalian prion disease in the fruit fly
Research funded by the NC3Rs shows potential to develop a fast and effective test to detect prion infectivity.
2016 Global 3Rs Award recipients announced
AAALAC and IQ Consortium recognise significant contributions towards the 3Rs.
What are the 3Rs?
The principles of the 3Rs (Replacement, Reduction and Refinement) were developed as a framework for humane animal research.

Pioneering Better Science


The NC3Rs is the UK's national organisation which leads the discovery and application of new technologies and approaches to replace, reduce and refine the use of animals for scientific purposes (the 3Rs).

We collaborate with scientists and organisations from across the life sciences sector, nationally and internationally, including universities, the pharmaceutical, chemical and consumer products industries, other research funders, and regulatory authorities.

We fund 3Rs research, training and career development, support open innovation and commercialisation of 3Rs technologies, and stimulate changes in policy, regulations and practice relating to the use of animals.

Keep in touch

Open calls

Submission date:
We are now inviting informal outlines to our new scheme which supports the adoption of alternative 3Rs models, tools and technologies.

Submission date:
The outline application form is now available on Je-S.