TalkScience at the British Library: the 3Rs
Join us at the British Library on Thursday 13 October where a panel of experts will discuss the use of animals in research and the 3Rs.
NC3Rs Summer School 2016
19 PhD students met at the University of York in July, to discuss their 3Rs-related research and participate in various scientific activities.
2016 CRACK IT Challenges competition now open
£2.8 million available for four new Challenges.
New video tutorial: mouse handling made easier
Our latest resource focuses on best practice in the handling of laboratory mice.
Using personalised organoids to reduce animal testing
A blog on Hayley Francies' research, highly commended in our 3Rs Prize competition.
Explore the science we fund
Our programmes are divided into research funded through grants & early career awards, CRACK IT & office led research.
NC3Rs/ABPI collaboration
New project will focus on the use of the second species in regulatory toxicology studies.
Resources from the NC3Rs
We provide an extensive library of 3Rs resources including guidelines, practical information and themed hubs.
Highlighting best practice in laboratory animal euthanasia
A new report from the second meeting between the NC3Rs and Newcastle University.
2016 Primate Welfare Meeting
A key event for researchers, veterinarians, technologists and others involved with the care and use of non-human primates.
Expert opinion pieces on genetically altered mice
A series from Dr Sara Wells, Director of the Mary Lyon Centre, MRC Harwell Institute.
What are the 3Rs?
The principles of the 3Rs (Replacement, Reduction and Refinement) were developed as a framework for humane animal research.

Pioneering Better Science


The NC3Rs is the UK's national organisation which leads the discovery and application of new technologies and approaches to replace, reduce and refine the use of animals for scientific purposes (the 3Rs).

We collaborate with scientists and organisations from across the life sciences sector, nationally and internationally, including universities, the pharmaceutical, chemical and consumer products industries, other research funders, and regulatory authorities.

We fund 3Rs research, training and career development, support open innovation and commercialisation of 3Rs technologies, and stimulate changes in policy, regulations and practice relating to the use of animals.

Keep in touch

Open calls

Submission date:
We are now accepting applications to our Two Phase Challenges, Osteo-Chip and Retinal 3D.

Submission date:
We are now accepting applications to our Single Phase Challenges, EASE and Maximise.