Latest news and blogs
Tuesday 12 April 2016
They say you can’t teach an old dog new tricks. But what about scientists and new procedures?
Wednesday 06 April 2016
We are launching a new series of monthly blog posts by our Chief Executive, Dr Vicky Robinson. In her first blog she focuses on the growing interest in the issues surrounding experimental design, arguably the most important aspect of any scientific study. The design, analysis and reporting of animal research...
Tuesday 29 March 2016
A study published in Nature reported the creation of brain organoids that mimic the developing human cerebrum for the very first time. One of the authors, Dr Madeline Lancaster, who now works at the MRC Laboratory of Molecular Biology, has recently won the annual NC3Rs 3Rs Prize for this work.
Wednesday 23 March 2016
A new study has shown that introducing physiologic cues to the in vitro culture of hepatocyte-like cells (HLCs) makes them a more relevant hepatocyte model that can be used in non-animal liver toxicity testing. The paper, published last week in Archives of Toxicology, is the result of a collaboration between...
Friday 18 March 2016
The work of the NC3Rs is increasingly international. We continue to maintain our focus as the UK’s national centre on the 3Rs, but as our portfolio of office-led data sharing activities has grown, so too has the number of overseas partners that we collaborate with. More than half of the pharmaceutical and...
Tuesday 15 March 2016
A study describes a new method to grow a drug resistant sub-population of cancer stem cells (CSCs) in vitro, providing an opportunity to screen compounds that target these cells using fewer animals.
Wednesday 09 March 2016
Three projects have each been awarded £30,000 seed funding, through the NC3Rs CRACK IT Solutions partnering programme, to support collaborations which will help develop, validate and test technologies with 3Rs potential. The programme links technology developers with researchers and organisations that can add...
New CRACK IT Solution: Extrapolating in vitro to in vivo toxicity for predicting effects on growth in rats and mice
Tuesday 08 March 2016
Researchers at the University of York are seeking partners with expertise in mammalian cell culture to develop novel mathematical approaches for in vitro to in vivo extrapolation. Such models developed as part of a suite of tests have the potential to reduce the use of animals in chronic toxicity studies. The...
Monday 29 February 2016
Three pieces of outstanding published research with 3Rs impacts have been given awards in this year’s 3Rs Prize competition, run by the NC3Rs, and sponsored by GlaxoSmithKline (GSK). The Prize ceremony is taking place today (29 February) with 150 guests from across the scientific community attending. The 3Rs...
Latest CRACK IT Challenges: funding innovative technologies with 3Rs benefits and business potential
Monday 29 February 2016
Six teams have been awarded funding in Phase 1 of the latest NC3Rs CRACK IT Challenges competition, a challenge-led competition run in collaboration with the UK’s innovation agency, Innovate UK, using its Small Business Research Initiative (SBRI). CRACK IT Challenges bring together industry, academia and SMEs...
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