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Biomembrane activity model

Professor Andrew Nelson (University of Leeds) is seeking partners to help develop and validate his technology to screen compounds, polymers and nanoparticles in a high throughput configuration to identify chemicals and drugs with potential biomembrane permeability and toxicity. The technology consists of a miniaturised microfluidic flow system comprising a phospholipid sensor element that can be tailored to respond to selected chemicals. This technology is more biologically relevant, faster and cheaper than current in silico methods for measuring biomembrane activity. As such, it has the potential to greatly reduce the number of compounds entering animal studies that will fail due to undesirable biomembrane toxicity. For further information please see the flyer.