News

A team led by Dr Amer Jamalpoor at Toxys has proceeded to the next stage of the CrossDART CRACK IT Challenge to develop and qualify multi-species in vitro assays to reduce reliance on in vivo embryo-fetal developmental studies.

As we open the call for 2025 CRACK IT Challenge ideas, we sat down with the Chair of our CRACK IT Advisory Panel, Professor Mike Capaldi, to discuss innovation and the 3Rs.

Do you have an idea to improve R&D and refine or reduce your reliance on in vivo studies? We want to hear from you.

A team led by Dr Adam Polak at the Fraunhofer UK Research Ltd has been awarded £100k to develop a non-invasive and non-toxic method to identify individual mice from birth.

The 2024 CRACK IT Challenges Competition is now closed.

Two Challenges in the areas of new approach methodologies (NAMs) for avian toxicity testing and to improve the post-operative care of rodents have been launched.

Six teams have been awarded up to £100k each in CRACK IT Challenge funding to deliver proof-of-concept studies to address two Challenges that aim to accelerate the development and use of New Approach Methodologies.

A team led by Professor Toni Cathomen at the University of Freiburg (Germany) has secured £1M of CRACK IT Challenge funding to develop an approach to evaluate the tumourigenicity of human engineered T cell therapies. 

Sponsor a Challenge: overcome scientific barriers with 3Rs-driven solutions. We are looking for stakeholders from across the biosciences to submit their ideas for new CRACK IT Challenges.