Replacement, Reduction and Refinement
Guidelines, practical information, publications, video and training materials to help you put the 3Rs into practice.
We fund world class researchers to develop predictive, reliable and humane 3Rs approaches.
Details of NC3Rs projects, including grants, early career awards and work led by our staff.
What are the 3Rs? How many animals are used in research? Find answers to these questions and more.
Latest news
The ARRIVE study plan is a freely available resource to assess the rigour and improve the transparency of planned animal research.
£10M will be available to support interdisciplinary research clusters.
We have made the first Network primer awards to our 3Rs Network members to establish collaborations and apply 3Rs technologies to new research questions.
Explore the evolving relationship between genetic modification and the 3Rs over the past two decades in our article in the Genetics Society magazine.
Analysis led by the NC3Rs aims to inform new endocrine disruption testing requirements in the EU to avoid substantially increasing animal use and resource.
Our total commitment for project grants over the past twenty years has now surpassed £50M, supporting 3Rs method development, characterisation and dissemination.
Discover 3Rs innovations from the NC3Rs
Bringing together expertise from different sectors and disciplines to deliver readily available and easily deployed 3Rs models and tools that are more predictive and cost-effective than current animal models.
