Semi-automated spontaneous recognition tasks
A continuous trials apparatus for multiple spontaneous recognition tasks with no handling required between trials.
Tasteless tamoxifen to refine transgenic mouse studies
Tamoxifen micropellets with a taste-masking coating for oral administration and efficient cre-recombination from Fluid Pharma.
Precise, low-dead space needle to refine preclinical injections in mice
Precision Injection System: handheld syringe and needle that minimises injectate waste and improves dosing accuracy, from Active Needle Technologies.
In silco model to predict human respiratory irritation
A web-based QSAR model to identify candidate chemicals that cause human respiratory irritation based on their structure.
In silico platform to identify and analyse developmental and reproductive toxicity pathways
Xpaths: an integrative platform for the assessment of developmental and reproductive toxicology from Vivaltes, to predict the outcomes of regulatory studies.
Microfluidic culture system to improve implantation rates of early stage embryos
IVF Micro: microfluidics to improve the developmental competence of mouse embryos cultured in vitro for non-surgical embryo transfer.
In vitro retinal model for better prediction of in vivo outcomes
Light responsive retinal organoids containing key cell types generated from human stem cells from NewCells Biotech.
3D model of human osetoarthritic joint
In vitro osteochondral model by Alcyomics, incorporating osteoblasts and chondrocytes for use in drug development pipelines.
In vitro genotoxicity assessment platform for gene therapy
hInGeTox: preclinical viral vector safety assessment service for gene therapy producers from TestAVec .
In silico tools to predict skin and eye irritation and corrosivity
iSafeRat: high accuracy QSARs to predict toxicological endpoints for petrochemical substances suitable for regulatory purposes.
3D human stem cell-based model to assess neurotoxicity
A microfluidic model of human stem cell-derived neurons and astrocytes by Mimetas for applications in central nervous system safety pharmacology.
Human kidney model for drug-induced nephrotoxicity screening
Perfused epithelial kidney model by Mimetas for early in vitro drug screening.
Cells, tissue and software to assess cardiovascular safety
A suite of assays using cardiac myocytes to assess the cardiac liabilites of drugs.
Human stem cell model of tau pathology
Human induced pluripotent stem cell lines with tau gene mutations as a human-relevant model to study Alzheimer’s disease, available from EBiSC.
Toxiocological assessments using non-mammalian species
Data science and wet lab testing services by Vivaltes B.V. to assess developmental and reproductive toxicity.