Winners of the 2011 CRACK IT Challenges competition have been announced by the NC3Rs at the NC3Rs Annual Science Review on 28 February 2012. The five Challenges are funded by NC3Rs with in-kind contributions from industry sponsors AstraZeneca, Huntingdon Life Sciences, Lilly, Syngenta and Unilever.
The winners are:
Wireless recording of the electrophysiology of cognition in psychiatric disease models
Dr Esther Rodriguez-Villegas of Imperial College and Ervitech.
Rodent Big Brother: automated recording of rodent activity and temperature in the home cage
Professor Douglas Armstrong from Actual Analytics together with colleagues from TSE Systems and Professor Judith Pratt of the University of Strathclyde.
Improving the predictive capacity of in vitro cytokine release assays to reduce animal use and drug attrition
Professor Martin Glennie from the University of Southampton with collaborators from the University of York.
Improved in vitro to in vivo extrapolation in chemical safety risk assessment of human systemic toxicity
Dr Dominic Williams, University of Liverpool, working in collaboration with Dr Marianne Ellis, University of Bath, Dr John Ward, Loughborough University, Dr Rebecca Shipley, University of Oxford, Dr Steven Webb, University of Strathclyde, and Dr Iain Gardner, Simcyp.
BADIPS: Generating human induced pluripotent stem cells (iPS cells) to study bipolar affective disorder
Professor Andrew McIntosh from the University of Edinburgh in collaboration with the University of Cambridge and Roslin Cells.
More information on these challenges is available here.