CRACK IT winners to be announced

Winners of the 2011 CRACK IT Challenges competition will be announced by NC3Rs at the NC3Rs Annual Science Review on 28 February 2012.  The five Challenges are funded by NC3Rs with in-kind contributions from industry sponsors AstraZeneca, Huntingdon Life Sciences, Janssen, Lilly, Syngenta and Unilever. 

The Challenges are:

• Wireless recording of the electrophysiology of cognition in psychiatric disease models
• Rodent Big Brother: automated recording of rodent activity and temperature in the home cage
• Improving the predictive capacity of in vitro cytokine release assays to reduce animal use and drug attrition
• Improved in vitro to in vivo extrapolation in chemical safety risk assessment of human systemic toxicity
• BADIPS: Generating human induced pluripotent stem cells (iPS cells) to study bipolar affective disorder