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Call open for 2024 CRACK IT Challenges

23 November 2023

We are looking for experts with research questions that could be solved with a 3Rs driven approach. 

Ideas can come from industry, academic and the charitable sectors and be developed into a new Challenge for our 2024 competition. Challenges are pitched to the bioscience sector to develop new technologies which deliver 3Rs, scientific and business benefits.

Working with us on a CRACK IT Challenge gives you the opportunity to define the aims and deliverables, and support the success of the Challenge by collaborating with the Challenge winners and providing in-kind contributions (e.g. expertise, compounds, data or in-house testing) and end-user input.

Do you have an idea to improve R&D and refine or reduce reliance on animal models? Contact us at

CRACK IT Challenges fund collaborations between industry, academia and SMEs to support the development of 3Rs products and services that are directly targeted to meet end-user needs . Since 2011, CRACK IT has launched 47 Challenges, invested over £34M and worked with 51 Sponsors and Partners in projects that have developed technologies to address an unmet need using 3Rs driven approaches.

If you have a research question that you would like a CRACK IT Challenge to solve, please visit our website  for further information on how to submit your idea, the process and the role of a Sponsor or contact the CRACK IT team directly at The deadline for new Challenge submissions is Friday 16 February 2024

Read more about being a CRACK IT Challenge Sponsor 

Please get in touch with us, the CRACK IT team are happy to explore your early ideas with you.