Tasteless tamoxifen to refine transgenic mouse studies Tamoxifen micropellets with a taste-masking coating for oral administration and efficient cre-recombination from Fluid Pharma.
Precision Injection System Active Needle Technology Ltd has developed and evaluated a Precision Injection System for use in preclinical injections of rodents.
In silco model to predict human respiratory irritation A web-based QSAR model to identify candidate chemicals that cause human respiratory irritation based on their structure.
In silico platform to identify and analyse developmental and reproductive toxicity pathways Xpaths: an integrative platform for the assessment of developmental and reproductive toxicology from Vivaltes, to predict the outcomes of regulatory studies.
Microfluidic culture system to improve implantation rates of early stage embryos IVF Micro: microfluidics to improve the developmental competence of mouse embryos cultured in vitro for non-surgical embryo transfer.
In vitro retinal model for better prediction of in vivo outcomes Light responsive retinal organoids containing key cell types generated from human stem cells from NewCells Biotech.
3D model of human osetoarthritic joint In vitro osteochondral model by Alcyomics, incorporating osteoblasts and chondrocytes for use in drug development pipelines.
Semi-automated spontaneous recognition tasks A continuous trials apparatus for multiple spontaneous recognition tasks with no handling required between trials.
In vitro genotoxicity assessment platform for gene therapy hInGeTox: preclinical viral vector safety assessment service for gene therapy producers from TestAVec .
In silico tools to predict skin and eye irritation and corrosivity iSafeRat: high accuracy QSARs to predict toxicological endpoints for petrochemical substances suitable for regulatory purposes.
3D human stem cell-based model to assess neurotoxicity A microfluidic model of human stem cell-derived neurons and astrocytes by Mimetas for applications in central nervous system safety pharmacology.
Human kidney model for drug-induced nephrotoxicity screening Perfused epithelial kidney model by Mimetas for early in vitro drug screening.
Morph_ONE An in vitro cell painting assay that can differentiate alveolar macrophage responses allowing insight into the response of the immune system in the lungs to inhaled chemical products.
Cells, tissue and software to assess cardiovascular safety A suite of assays using cardiac myocytes to assess the cardiac liabilites of drugs.
Human stem cell model of tau pathology Human induced pluripotent stem cell lines with tau gene mutations as a human-relevant model to study Alzheimer’s disease, available from EBiSC.
Toxiocological assessments using non-mammalian species Data science and wet lab testing services by Vivaltes B.V. to assess developmental and reproductive toxicity.
