News

Open for applications: four new Challenges have been announced in this year’s open innovation funding competition.

Funding for 18 months has been awarded to a team at KREATiS to deliver the CRACK IT Challenge Thyroid Tox.

esqLABS have been awarded the Phase 2 contract to develop a NAMs-driven in silico framework to predict toxicological endpoints in the dog.

19 January 2023

Two teams have been awarded £100k funding each to carry out Phase 1 proof-of-concept studies to establish an in vitro assay system to evaluate the tumourigenicity of genetically engineered T cell therapies*.

Do you have a great idea to drive innovation in research and development and have a real-world impact on the 3Rs?

aQuaTox-Solutions GmbH has been awarded funding to deliver the second phase of the SAFE CRACK IT Challenge.

CRACK IT Challenges is the NC3Rs open innovation funding competition which brings together industry, academia and SMEs to deliver ready-to-use products and services to replace, reduce and refine animal use. Challenges are developed in collaboration with Sponsors who provide in-kind contributions and/or co-funding to support development of the Challenge product. 

Two Challenges are now open for applications for the 2022 CRACK IT competition, focusing on in vitro safety assessment of CAR-T cell therapies and in silico tools for endocrine disruption.

Development of an immune response assay, adaptation of OECD test guideline assays and development of an in vitro skeletal muscle injury model.