Challenge 40 Virtual Second Species Development of virtual dog tissues and organs for chronic toxicity studies.
Challenge 37 STRATIS A human-relevant and high throughput in vitro or ex vivo platform that recapitulates the complex structures of skeletal muscle and the pathology of significant injury to them.
Challenge 36 Animal-free in vitro Replacement of animal-derived reagents in an established human cell-based in vitro assay associated with an OECD Test Guideline.
Challenge 34 Sharp and to the Point Developing needles for high throughput and critical compound administration in mice.
Challenge 33 CleanCut Animal free tumourigenicity assessment of genome edited human haematopoietic stem cells.
Challenge 32 Transgene Track Development of a sensitive, absolute quantification method for tracking AAV gene therapies and CAR-T cells in vivo.
Challenge 30 RaTS A handheld device for objective monitoring of rheumatoid arthritis (RA) progression in awake rodents.
Challenge 29 ImmuLiver An immunologically-competent in vitro model of the human liver for the assessment of Yellow Fever (YF) vaccine attenuation.
Challenge 28 RespiraTox An in silico QSAR-based tool that reliably predicts the human respiratory irritancy potential of chemicals.
Challenge 27 DoCE Improved tools to better quantify and control the exposure of chemicals over a wide range of in vitro assay systems.
Challenge 26 DARTpaths Mapping developmental and reproductive toxicity (DART) genes and pathways for cross-species comparison of toxic compound effects.
