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Challenges

Challenge 39
Tat-Fit
Tasteful tamoxifen for inducible transgenesis.
2020
Challenge 38
Mouse MApp
An application to monitor the welfare of mice.
2020
Challenge 37
STRATIS
A human-relevant and high throughput in vitro or ex vivo platform that recapitulates the complex structures of skeletal muscle and the pathology of significant injury to them.
2020
Challenge 36
Animal-free in vitro
Replacement of animal-derived reagents in an established human cell-based in vitro assay associated with an OECD Test Guideline.
2020
Challenge 35
In vitro TDAR
A human immune response assay for the assessment of immune modulation
2020
Challenge 34
Sharp and to the Point
Developing needles for high throughput and critical compound administration in mice.
2019
Challenge 33
CleanCut
Animal free tumourigenicity assessment of genome edited human haematopoietic stem cells.
2019
Challenge 32
Transgene Track
Development of a sensitive, absolute quantification method for tracking AAV gene therapies and CAR-T cells in vivo.
2019
Challenge 31
Moshers
A device to accurately measure individual food intake in group-housed mice. 
2018
Challenge 30
RaTS
A handheld device for objective monitoring of rheumatoid arthritis (RA) progression in awake rodents. 
2018
Challenge 29
ImmuLiver
An immunologically-competent in vitro model of the human liver for the assessment of Yellow Fever (YF) vaccine attenuation.
2018
Challenge 28
RespiraTox
An in silico QSAR-based tool that reliably predicts the human respiratory irritancy potential of chemicals.
2017
Challenge 27
DoCE
Improved tools to better quantify and control the exposure of chemicals over a wide range of in vitro assay systems.
2017
Challenge 26
DARTpaths
Mapping developmental and reproductive toxicity (DART) genes and pathways for cross-species comparison of toxic compound effects.
2017
Challenge 25
Maximise
An in silico model to classify agrochemical mixtures to fulfil acute GHS Classification and Labelling requirements for acute oral toxicity, skin and eye irritation.
2016
Challenge 24
EASE
An approach that improves the implantation rates of early stage embryos when combined with extended in vitro culture and non-surgical embryo transfer techniques in the generation of transgenic mice.
2016

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