Webinar and video

Non-animal approaches across Europe

This webinar series from The Togeth3R Consortium of European 3Rs centres showcases advances in model development and opportunities to apply non-animal approaches in research fields associated with high levels of animal use.

The webinars took place in February and March 2025, featuring researchers from institutions across Europe in four sessions focusing on infection and immunity, oncology, neuroscience and cardiovascular science.

Non-animal approaches in infection and immunity

A cross-species ex vivo assay for tuberculosis vaccine testing

Dr Rachel Tanner – University of Oxford, UK

Infection, innate immune signalling and cancer in the gut: Organoids as models

Prof Sina Bartfeld – Technische Universität Berlin, Germany

Building a virtual twin of the rheumatic joint

Prof Anna Niarakis – University of Toulouse III, Paul Sabatier, Center of Integrative Biology, France

Non-animal approaches in oncology

AirLiwell technology: Development and perspectives in oncology replacement

Dr Sanae El Harane – University of Geneva, Switzerland

Patient-derived leukaemia organoids

Dr Deepali Pal – University of Bristol, UK

Tissue-on-chip models using patient biopsies to study patient response

Prof John Greenman – University of Hull, UK

Non-animal approaches in neuroscience

Brain organoids to study Alzheimer’s disease: A comparative approach

Prof Ivan Nalvarte – Karolinska Institutet, Sweden

Human neuronal models of Alzheimer’s disease for understanding disease mechanisms and developing novel therapies

Prof Selina Wray – University College London, UK

BRAINCELL, a computational platform to explore in silico realistic 3D brain cells and their interactions

Prof Dmitri Rusakov and Dr Leonid Savtchenko – University College London, UK

Non-animal approaches in cardiovascular science

Advanced heart-on-a-chip models in disease modelling and drug screening

Prof Milica Radisic – University of Toronto, Canada/Berlin Institute of Health at Charité, Germany

Human stem cell-derived cardiomyocytes for cardiotoxicity screens

Prof Chris Denning – University of Nottingham, UK

High fidelity computational approaches to model cardiovascular diseases

Dr Caglar Ozturk – University of Southampton, UK