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NC3Rs | 20 Years: Pioneering Better Science

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38 results

Using exposure science to refine and reduce animal use, and support the uptake of new approach methodologies

A lister hooded rat (black head white body) seen in a standard rat housing cage. The rat is standing on a plastic box and is looking out of the open cage lid.

Archiving can provide a back-up to production colonies, minimise genetic drift, reduce the need for tick-over colonies and preserve valuable models.

A white sperm and egg icon on a blue background

Techniques for blood sampling in laboratory animal species to ensure the most appropriate technique is chosen.

Five needles with empty syringes on a pale blue background

Guidelines on implementing the 3Rs in both field and captive studies.

Two wild frogs

Reducing and refining acute toxicity tests in the pharmaceutical and chemicals industries.

A white mouse on a technician's gloved hands

Providing an evidence base to refine and reduce the use of vertebrates in (regulatory) ecotoxicology studies

A group of young rainbow trout