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NC3Rs: National Centre for the Replacement Refinement & Reduction of Animals in Research

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Keep up to date with the latest news from the NC3Rs, including the researchers we fund. Follow us on social media and subscribe to our newsletter to get the latest updates directly.

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Hear how lecturers at the University of Nottingham are using the Experimental Design Assistant (EDA) as an engaging and practical way to teach experimental design.

Early career researchers at a workshop on experimental design.

The ARRIVE study plan is a freely available resource to assess the rigour and improve the transparency of planned animal research.

The ARRIVE study plan

Our total commitment for project grants over the past twenty years has now surpassed £50M, supporting 3Rs method development, characterisation and dissemination.

Centrifuge tubes in a orange rack

Our Experimental Design Assistant (EDA) helps you to design robust and meaningful animal experiments. With a wealth of information, features and tools, here are our tips to help you make the most of the EDA.

A diagram showing how the EDA can be used to represent a two group comparison experiment. The EDA works by dragging and dropping 'nodes' which appear as coloured shapes. These are then connected with arrows or ‘links’ showing how different parts of an experiment relate to each other. The EDA then uses computer-based logical reasoning to provide feedback on the experimental design.

Our latest impact stories feature three replacement approaches developed through NC3Rs funding that were the first in vitro models validated to replace animal use for specific experiments in their research areas.

Three sets of icons. Left to right: Bone, cancer cells, 96 well plate.

We are launching a new funding opportunity through a strategic collaboration with BBSRC to help researchers commercialise their 3Rs tools and technologies.

ICURe Innovate UK and BBSRC