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Our Project grant scheme is open for applications, supporting the development of new 3Rs approaches and technologies!

NC3Rs: National Centre for the Replacement Refinement & Reduction of Animals in Research
Pioneering better science

Replacement, Reduction and Refinement

A UK-based scientific organisation dedicated to helping the research community worldwide to identify, develop and use 3Rs technologies and approaches.
Our mission
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Guidelines, practical information, publications, video and training materials to help you put the 3Rs into practice.

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We fund world class researchers to develop predictive, reliable and humane 3Rs approaches.

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Details of NC3Rs projects, including grants, early career awards and work led by our staff.

Two researchers look at a sample in a Petri dish

What are the 3Rs? How many animals are used in research? Find answers to these questions and more.

Two white rats in an enriched cage containing cardboard tunnels and paper towels.

Latest news

The latest impact stories feature a model of early-stage lung cancer, an artificial human blood vessel to study blood clotting in vitro and a 3D human cell culture model to evaluate and screen treatments for glioblastoma.

Illustration showing the various organs that an organ-on-a-chip can model, including the retina, brain, heart, lungs, kidneys and intestines.
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Upcoming events

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CRACK IT

Discover 3Rs innovations from the NC3Rs

Bringing together expertise from different sectors and disciplines to deliver readily available and easily deployed 3Rs models and tools that are more predictive and cost-effective than current animal models.

Discover our CRACK IT Challenges funding competition
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