Welfare of non-human primates
Resources to refine the use of non-human primates.
How to pick up a mouse
Resources on the implementation of non-aversive methods for handling mice to reduce stress and anxiety.
Our new newsletter providing animal technicians with the latest news from the NC3Rs.
New 3Rs training resource
Our new video presentation provides an introduction to the 3Rs and their scientific importance.
2018 CRACK IT Challenge competition open
Apply by 7 November (ImmuLiver and RaTS) or 14 November (Moshers).
2019 Skills and Knowledge Transfer grant call now open
£550k available including £150k from CRUK. Outline deadline 4pm, 23 November.
2018 International 3Rs Prize open for applications
Our annual 3Rs Prize highlights outstanding and original research with a high potential 3Rs impact. Apply by 4pm on 5 December.
Public engagement awards scheme: open rolling call
Grant holders can apply for an award of up to £1,500 to engage the public in 3Rs research.
Visit the NC3Rs Gateway
Our open access publication portal, hosted by F1000Research, will maximise the 3Rs impact of NC3Rs-funded research.
Mouse handling workshop
This free workshop on 26 November will provide support for adopting the refined techniques in your establishement. Register by 12 November.
Tickling rats: an enrichment to improve rodent welfare
Exploring a novel technique for refining experiments through social enrichment.
Re-use of needles: is this an indicator of a culture of care?
This guest blog post explores the issue of re-using needles in day-to-day practice.

The NC3Rs: Pioneering better science

If you are a scientist, animal technician, veterinarian, regulator, funder or policy maker, the NC3Rs can help you to:

  • Drive scientific and technological developments that replace, reduce or refine the use of animals in research (the 3Rs)
  • Ensure your animal experiments are as robust and reproducible as possible
  • Provide the best welfare for laboratory animals


Science-led and evidence-based, we fund research and early careers, foster collaborations between universities and industry to develop and commercialise 3Rs technologies, and provide information on the latest advances to put the 3Rs into practice.

Keep in touch

Latest news & blogs

Announcing a new collaboration with Medicines Discovery Catapult

The ‘Technologies to Tools’ funding scheme will accelerate the translation of 3Rs technologies into industry-ready products and services.

Discussing the future of amphibians in research

Read the report from the NC3Rs/ZSL workshop on addressing the animal welfare challenges facing amphibian research.

NC3Rs-funded technology wins international award

Professor Esther Rodriguez-Villegas from Imperial College London is recognised for TaiNi, a device for refined recording of neural activity in mice.

UCL scientists develop welfare-friendly method for training macaques

Use of a touchscreen in their home enclosure leads to high performance levels in macaques without the need for restraint.