Guidelines, practical information, publications, video and training materials to help you put the 3Rs into practice.
We fund world class researchers to develop predictive, reliable and humane 3Rs approaches.
Details of NC3Rs projects, including grants, early career awards and work led by our staff.
What are the 3Rs? How many animals are used in research? Find answers to these questions and more.
Latest news
We have published a report to increase the uptake of non-animal derived antibodies and non-antibody affinity reagents by the research community.
A new paper makes recommendations for dose selection in developmental and reproductive toxicity studies to avoid unnecessary animal suffering, reduce animal use and maintain the highest standards of human health protection.
Working directly with scientists, technicians and research institutions to accelerate the uptake of the 3Rs, our new regional training offering is available free of charge across the UK.
Our Regional Programme Manager, Dr Ellen Forty, speaks to individuals across three UK research establishments about the unique focus the role of a ‘3Rs Champion’ brings to their local research environment.
Discover how the NC3Rs works to address the use of dogs in research and replace the use of animals in toxicity testing with non-animal methods, two topics being debated in Parliament later today.
Working with the British Toxicology Society we have identified actions to optimise opportunities presented from exiting the EU to develop a world-leading regulatory framework that firmly embeds the 3Rs in chemical safety testing.
Discover 3Rs innovations from the NC3Rs
Bringing together expertise from different sectors and disciplines to deliver readily available and easily deployed 3Rs models and tools that are more predictive and cost-effective than current animal models.