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NC3Rs | 20 Years: Pioneering Better Science
Pioneering better science

Replacement, Reduction and Refinement

A UK-based scientific organisation dedicated to helping the research community worldwide to identify, develop and use 3Rs technologies and approaches.
Our mission
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Guidelines, practical information, publications, video and training materials to help you put the 3Rs into practice.

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We fund world class researchers to develop predictive, reliable and humane 3Rs approaches.

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Details of NC3Rs projects, including grants, early career awards and work led by our staff.

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What are the 3Rs? How many animals are used in research? Find answers to these questions and more.

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Latest news

Discover how the NC3Rs works to address the use of dogs in research and replace the use of animals in toxicity testing with non-animal methods, two topics being debated in Parliament later today.

Portrait of Dr Vicky Robinson, Chief Executive, NC3Rs.
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Upcoming events

Join us to launch our new Cardiovascular Network, which brings together cross-sector scientists developing 3Rs models in cardiovascular research.

Join us to launch the NAMs Network and engage with stakeholders working to accelerate the use of new approach methodologies.

View all NC3Rs events
CRACK IT

Discover 3Rs innovations from the NC3Rs

Bringing together expertise from different sectors and disciplines to deliver readily available and easily deployed 3Rs models and tools that are more predictive and cost-effective than current animal models.

Discover our CRACK IT Challenges funding competition
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