Congratulations to Dr Rickie Patani, winner of the 2018 International 3Rs Prize
Dr Patani was awarded this year's prize, sponsored by GSK, for a human stem cell model of motor neuron disease.
Tech3Rs: our animal technician newsletter
Sign up to receive free copies for UK facilities and stay up to date with the 3Rs.
2019 PhD Studentship call now open
The deadline to submit your informal outline is 4pm on 1 May.
Read our latest Research Review
The review profiles the work of 12 NC3Rs-funded scientists and its impacts on the 3Rs and beyond.
Discover publications from NC3Rs researchers
Visit our open access publication portal, hosted by F1000Research.
First out of the gate(way): studying Alzheimer’s in vitro
Exploring the 3Rs research behind the first paper on our F1000Research gateway.
What are the 3Rs and why are they important?
Our new video presentation has been designed for use in training and education.
Experimental design
Resources to help you improve the design and reporting of your in vivo research.
Tickling rats: an enrichment to improve rodent welfare
Exploring a novel technique for refining experiments through social enrichment.

The NC3Rs: Pioneering better science

If you are a scientist, animal technician, veterinarian, regulator, funder or policy maker, the NC3Rs can help you to:

  • Drive scientific and technological developments that replace, reduce or refine the use of animals in research (the 3Rs)
  • Ensure your animal experiments are as robust and reproducible as possible
  • Provide the best welfare for laboratory animals


Science-led and evidence-based, we fund research and early careers, foster collaborations between universities and industry to develop and commercialise 3Rs technologies, and provide information on the latest advances to put the 3Rs into practice.

Keep in touch

Latest news & blogs

A Pint of 3Rs Science

Book your tickets now for our 3Rs-themed evenings, taking place in pubs across the UK this May as part of Pint of Science 2019.

Behavioural assessment of wellness and pain in macaques

NC3Rs-funded research has identified behavioural indicators of wellness and pain for macaques, paving the way for more accurate assessment of their welfare.

Efficient transport box and chair training of rhesus macaques

A new paper explores how refined training methods reduce the amount of time needed to acclimatise monkeys to transport devices.

Stem cell model of motor neuron disease wins International 3Rs Prize 2018

Dr Rickie Patani from the Francis Crick Institute and UCL Queen Square Institute of Neurology led a multidisciplinary team in developing a model that avoids the use of animals.

New NC3Rs Research Review showcases 3Rs-focused science

Our latest Research Review profiles the work of 12 NC3Rs-funded scientists, exploring its impacts beyond the 3Rs.

Join our mouse handling Twitter chat on 5 March

Take this opportunity to ask questions about refined mouse handling methods and share your experiences via #3Rschat.