2018 International 3Rs Prize open for applications
Our annual 3Rs Prize highlights outstanding and original research with a high potential 3Rs impact. Apply by 4pm on 5 December.
Funding Panel vacancies
Join leading scientists in selecting the latest 3Rs advances.
2019 funding highlight notice
Supporting rodent and non-mammalian model organism users to form partnerships and develop new applications.
2018 CRACK IT Challenge competition open
Apply by 7 November (ImmuLiver and RaTS) or 14 November (Moshers).
New 3Rs training resource
Our new video presentation provides an introduction to the 3Rs and their scientific importance.
Primate Welfare Meeting (15 November 2018)
Registration for this year's meeting closes on Friday 26 October.
Listen to the "3 Minute 3Rs" podcast
We have teamed up with LabAnimal and the NA3RsC to bring you “3 Minute 3Rs”, a monthly podcast summarising the latest 3Rs news.
Public engagement awards scheme: open rolling call
Grant holders can apply for an award of up to £1,500 to engage the public in 3Rs research.
Visit the NC3Rs Gateway
Our open access publication portal, hosted by F1000Research, will maximise the 3Rs impact of NC3Rs-funded research.
Watch our 'Mouse handling made easy' webinar
Learn the benefits of non-aversive handling methods and tips on how to implement them.
Tickling rats: an enrichment to improve rodent welfare
Exploring a novel technique for refining experiments through social enrichment.
Re-use of needles: is this an indicator of a culture of care?
This guest blog post explores the issue of re-using needles in day-to-day practice.

The NC3Rs

If you are a scientist, animal technician, veterinarian, regulator, funder or policy maker, the NC3Rs can help you to:

  • Drive scientific and technological developments that replace, reduce or refine the use of animals in research (the 3Rs)
  • Ensure your animal experiments are as robust and reproducible as possible
  • Provide the best welfare for laboratory animals


Science-led and evidence-based, we fund research and early careers, foster collaborations between universities and industry to develop and commercialise 3Rs technologies, and provide information on the latest advances to put the 3Rs into practice.

Keep in touch

Latest news & blogs

Self-organising ‘gastruloids’ mimic early development of mouse embryos

A new 3D cell culture model has the potential to replace the use of mouse embryos in studying early development.

Culturing human cells to study fungal lung colonisation

New research from the University of Manchester helps build confidence in the use of non-animal approaches in studying fungal infectious disease.

First out of the Gate(way): a method for studying Alzheimer’s in vitro

We profile work by Dr Cara Croft and Dr Wendy Noble, whose paper was the first to pass peer review on our F1000Research Gateway.

2018 Challenges Competition is now open-Invitation to Tender

This year's competition consists of three Challenges identified jointly by the NC3Rs and Sponsors.