How to address toxicology information requirements for biocidal products without vertebrate testing under GB BPR

The session aims to support attendees improve the quality of their submissions to meet Great Britain Biocidal Products Regulation (GB BPR) information requirements without vertebrate testing and understand how these will be reviewed by the regulator.

Topics covered:

• Introduction to the biocidal products toxicology information requirements and Article 62 of the GB BPR.
• How to address the toxicology information requirements for various human health endpoints whilst minimising unnecessary animal testing, including the use of alternative approaches (e.g. bridging/read across, in vitro and in silico methods).
• The human health endpoints covered will include:
  • Acute oral toxicity.
  • Acute dermal toxicity.
  • Acute inhalation toxicity.
  • Skin irritation.
  • Eye irritation.
  • Skin sensitisation.