Registration for this meeting is now closed.
Including both sexes in your experiments is increasingly being expected by regulators, funders and publishers. The MRC has recently introduced the requirement to include both sexes in experimental design and analysis plans for future funding rounds. This joint webinar from the NC3Rs and the MRC will explore how to address common challenges when planning, conducting and analysing animal experiments involving both sexes. The webinar will give practical advice for including both sexes in experimental design and analysis. It will also cover husbandry and other considerations when working with animals of both sexes, and give practical tips to manage any issues.
Dr Natasha Karp
Director of Statistics, Data Sciences & Quantitative Biology, Discovery Sciences, R&D, AstraZeneca
Dr Sara Wells
Director, Mary Lyon Centre at MRC Harwell
The agenda for the workshop is below:
|10.00 - 10.05||
Welcome and introductions
Dr Esther Pearl, NC3Rs
|10.05 - 10.15||
MRC’s new expectations on the inclusion of sex in experimental design
Dr Stella Child, UKRI - MRC
|10.15 - 10.30||
Let’s talk about sex: addressing misconceptions and barriers to including both sexes
Dr Natasha Karp, AstraZeneca
|10.30 - 10.45||
Husbandry, phenotyping and other considerations
Dr Sara Wells, Mary Lyon Centre at MRC Harwell
|10.45 - 11.00||Q & A Session|
There will be an opportunity to ask questions after the webinar presentation. The webinar is free to attend.
Researchers and animal care staff are encouraged to attend and the webinar will be of particular interest to anyone that would like to start including both sexes in their experiments.
Other resources that can help when including both sexes are:
- The Experimental Design Assistant (EDA) provides guidance for considering sex when designing your studies. From why including both sexes is important, to the different ways you can account for sex in your analysis.
- The NIH has resources for integrating sex into research.
- Karp NA and Reavey N (2018). Sex bias in preclinical research and an exploration of how to change the status quo. Br J Pharmacol 176(21): 4107– 18. doi: 10.1111/bph.14539
- Miller LR et al. (2017). Considering sex as a biological variable in preclinical research. FASEB 31(1): 29–34. doi: 10.1096/fj.201600781r
Certificates of attendance are available on request. This webinar is accredited for 1 hour of CPD learning.