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Pint of Science is a worldwide science festival which brings researchers to your local pub/cafe/space to share their scientific discoveries with you - no prior knowledge required. This year, the NC3Rs are sponsoring events in Leeds, London and Birmingham. NC3Rs-funded scientists will be sharing the latest advancements and innovations in 3Rs research, and how their work is pioneering better science that replaces, reduces and refines the use of animals.
Join us at The Social in Leeds on 23 May to hear how two PhD researchers at the University of Leeds are using new technologies and innovative approaches to replace and reduce the use of animals in research. We would like to thank the Pint of Science team at the University of Leeds for hosting this event.
The 3Rs: Alternatives and Innovation in Animal Research
To affinity and beyond: diagnostics of the future
Izzie Gibson is working with Dr Christian Tiede to replace animal-derived antibodies with 'alternative binding proteins' called Affimers, in a range of cellular and molecular applications. Christian's Affimer proteins were highly commended in the 2017 International 3Rs Prize and Izzie's work builds on this success to broaden the application and impact of this replacement approach.
Three species, one gene: replacing mice in neuroscience
Jen Ogbeta's research in Dr Steven Clapcote's lab aims to replace mouse models of neurodevelopmental disorders. Typically, research uses mice with the same mutation as human patients. Jen is investigating using flies that share these same genetic changes to replace mice in research, better understand mechanisms of disease and support the development of new treatments.