Briefing paper: Improving translation and minimising animal use with human-relevant in vitro preclinical models
The NC3Rs has committed over £60M for research and innovation to develop human-based in vitro models that replace the use of animals, better recapitulate human physiology and disease and increase the efficiency of drug development.
Today the NC3Rs publishes a briefing paper outlining our work on human-based in vitro preclinical models. Over the past 20 years the NC3Rs has focused on replacing studies that involve large numbers of animals, high levels of animal suffering, or are poorly predictive in terms of their translatability or reproducibility. From a starting point of scientific excellence, we are developing the next generation of preclinical models and supporting the qualification, optimisation and uptake of in vitro alternatives.
Read and download the briefing paper in Our reports and reviews.