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New MRC/NC3Rs funding call for novel human in vitro models of complex disease

Organ-on-chip device

£10M will be available to support interdisciplinary research clusters. 

We are collaborating with the MRC, in partnership with BBSRC and EPSRC, to support interdisciplinary research clusters to drive the development, validation and/or adaptation of human in vitro models of complex disease that can replace the use of animals in academia and/or industry. Research clusters could include bioengineers, biologists, biophysicists, clinicians, computational scientists and industry scientists and should focus on disease areas of high unmet need and/or address common needs to impact multiple fields.  

The aim of the call is to generate clusters which will:

  • Improve understanding of human disease mechanisms and better support therapeutic development for disease intervention.
  • Overcome limitations of current in vivo and in vitro models to represent human pathophysiology and disease heterogeneity.
  • Accelerate the development, validation and uptake of technologies and methods to accurately and reproducibly model human disease and reduce the reliance on animal models.

Register for our joint webinar on Wednesday 16 October for more information about the scheme.

Further information about the scheme and application process is available on the MRC website.

Key dateFunding call stage
Wednesday 16 October 2024Prospective applicant webinar
Friday 6 December 2024Expression of interest deadline   
Wednesday 22 January 2025Applicant workshop
Thursday 20 March 2025Application deadline