A study describes a new method to grow a drug resistant sub-population of cancer stem cells (CSCs) in vitro, providing an opportunity to screen compounds that target these cells using fewer animals.
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Three projects have each been awarded £30,000 seed funding, through the NC3Rs CRACK IT Solutions partnering programme, to support collaborations which will help develop, validate and test technologies with 3Rs potential.
Researchers at the University of York are seeking partners with expertise in mammalian cell culture to develop novel mathematical approaches for in vitro to in vivo extrapolation.
Latest CRACK IT Challenges: funding innovative technologies with 3Rs benefits and business potential
Six teams have been awarded funding in Phase 1 of the latest NC3Rs CRACK IT Challenges competition, a challenge-led competition run in collaboration with the UK’s innovation agency, Innovate UK, using its Small Business Research Initiative (SBRI).
Three pieces of outstanding published research with 3Rs impacts have been given awards in this year’s 3Rs Prize competition, run by the NC3Rs, and sponsored by GlaxoSmithKline (GSK).
A new e-learning training package designed to help researchers and animal care staff identify signs of good and poor welfare in laboratory animals has been launched online.
Fish are commonly used in experiments to identify environmental hazards and pollutants in water.
Bovine tuberculosis (bTB) is one of the biggest challenges facing the cattle farming industry in the UK.
The ARRIVE guidelines were launched in 2010, and since their publication the scientific community have been using the guidelines to improve the reporting of animal research.
Invertebrates such as Drosophila melanogaster (the fruit fly) are used extensively in research on complex biological processes and disease mechanisms.
A new e-learning resource focusing on the assessment of laboratory animal welfare has been launched to help researchers and animal care staff to identify signs of good and poor welfare in research animals.
A collaborative research team looked at improving toxicity testing via in vitro tests, to enable faster and more efficient evaluation of chemical effects on human health without the use of animals.
A new tool to help authors find and use the most appropriate reporting guidelines has been launched by Penelope, a start-up company seeking to simplify the academic publishing process.
Since 2011, CRACK IT has showcased 21 Challenges, invested more than £14 million, and has connected more than 170 organisations from industry and academia in 20 new projects to develop innovative products to address bioscience needs.
The NC3Rs open innovation platform CRACK IT has awarded £1 million in its annual competition run in collaboration with the UK’s innovation agency, Innovate UK, using the Small Business Research Initiative (SBRI).
The NC3Rs and the British Heart Foundation partner to fund new PhD studentship awards.
The NC3Rs, in collaboration with the UK Regenerative Medicine Platform, Stevenage Bioscience Catalyst and the Non-Animal Technologies Special Interest Group (NAT SIG), held a workshop in April 2015 to explore the application of cutting edge cell and
Learn about the Mary Lyon Centre's non-profit mouse line archive, which supports scientists worldwide.
Dr Daniel Adams (pictured below), University of California San Francisco, describes the latest resource from the NC3Rs aimed at refining neuroscience experiments using non-human primates – the Chronic Implants Wiki – and why a wiki format was chosen.
Scientists from Royal Holloway University of London and University College London have identified a specific fatty acid, decanoic acid, to have potent anti-epileptic effects.
