An in vitro model for pain and neurogenic inflammation in the oro-facial region and upper airways Principal Investigator: Dr Fionnuala Lundy, Queen's University Belfast PhD Studentship
Neonatal BCG vaccination: screening for genetic factors that influence host-pathogen interactions and reducing and replacing the requirement for animal infection models in immune mechanism discovery Principal Investigator: Professor Melanie Newport, Brighton and Sussex Medical School PhD Studentship
Highly differentiated cultures of ferret airway epithelium for the study of respiratory viruses, including influenza Principal Investigator: Professor Wendy Barclay, Imperial College London Project grant
Developing a platform of in vitro models of asthmatic and healthy lung: an alternative to the use of animals in asthma research Principal Investigator: Dr Felicity Rose, University of Nottingham Strategic grant
FIGCS: An in vitro model to replace ecotoxicity testing of fish to pharmaceuticals Principal Investigator: Professor Christer Hogstrand, King's College London Project grant
A chronic model of epilepsy in organotypic brain slice cultures of the rat entorhinal cortex Principal Investigator: Professor Roland Jones, University of Bath Project grant
A tissue engineered construct to monitor mucosal immunity in asthma Principal Investigator: Professor Donna Davies, University of Southampton Strategic grant
Development of cell based assays as replacement assays for Botulinum toxins and antitoxins Principal Investigator: Dr Dorothea Sesardic, National Institute for Biological Standards and Control Project grant
Using the Drosophila fly intestine to investigate Wnt targets in vivo Principal Investigator: Dr Owen Sansom, University of Glasgow Project grant
Derivation of conditionally immortalised mouse DRG cell lines Principal Investigator: Dr Mohammed Nassar, University of Sheffield Project grant
Stem cell-derived cardiomyocytes for detection of cardiotoxicity in cancer therapeutics Principal Investigator: Professor Sian Harding, Imperial College London Project grant
A 3D tissue model of breast morphogenesis for replacing animals in testing for endocrine disrupting substances Principal Investigator: Professor Charles Vyvyan Howard, University of Ulster Project grant
The validation of defined genotoxic thresholds, leading to better in vitro risk assessments of carcinogenic potential Principal Investigator: Professor Gareth Jenkins, Swansea University PhD Studentship
An in vitro model system to assay kidney-pathogen interactions determining outcome of Candida albicans infection Principal Investigator: Dr Donna MacCallum, University of Aberdeen PhD Studentship
Replacement of animals in cancer drug development by using 3D in vitro functional assays for increased predictive power Principal Investigator: Dr Louis Chesler, Institute of Cancer Research Project grant
Transgenic ES Cell Differentiation Systems to replace Transgenic Mouse Analysis of Tissue Specific Regulatory Elements Principal Investigator: Dr Berthold Gottgens, University of Cambridge Project grant
Reducing and replacing mouse use to model the human platelet response in vivo Principal Investigator: Dr Michael Emerson, Imperial College London Project grant
A compartmentalised chamber for the in vitro study and manipulation of axon degeneration Principal Investigator: Professor Victor Perry , University of Southampton Project grant
Drosophila as a model for Alzheimer's disease Principal Investigator: Dr Kevin Moffat, University of Warwick Project grant
Replacing, refining and reducing animal usage in epilepsy research using a non-sentient model Principal Investigator: Professor Robin Williams, Royal Holloway University of London Project grant