Optimisation and validation of 3D models of progressive human lung fibrosis Principal Investigator: Dr Joseph Bell, University of Southampton Fellowship
INDUCE-seq: a novel tool for next generation risk assessment Principal Investigator: Professor Simon Reed, Cardiff University PhD Studentship
Using ex vivo organotypic cultures to investigate donor cell integration in the gut Principal Investigator: Dr Conor McCann, University College London Project grant
In vitro, off-host, rearing of the poultry red mite to supply parasites for development of new control methods Principal Investigator: Dr Alasdair Nisbet, Moredun Research Institute Project grant
A Drosophila single-cell resource for brain metabolism research Principal Investigator: Dr Alex Gould, The Francis Crick Institute Project grant
Drug risk assessment and repurposing using biomimetic chromatography and body-on-chip technology Principal Investigator: Dr Adriana Tavares, University of Edinburgh PhD Studentship
Establishment of novel macrophage cell lines to study the pathogenesis of respiratory bacterial pathogens in lung alveolar macrophages Principal Investigator: Dr Gyorgy Fejer, University of Plymouth Partnerships and impact awards
Direct replacement of secondary antibodies by Affimer proteins Principal Investigator: Dr Christian Tiede, University of Leeds PhD Studentship
Development of a Drosophila-based platform to replace and reduce animal experimentation in epilepsy research Principal Investigator: Dr Manolis Fanto, King's College London Project grant
Preneoplastic Pancreatic (PanIN) Organoids as an in vitro Model of Pancreatic Cancer Progression Principal Investigator: Dr Pedro Perez-Mancera, University of Liverpool Project grant
Developing stem cell-derived macrophages to study host pathogen interactions and advance strategies to combat globally important disease in the pig Principal Investigator: Dr Thomas Burdon, University of Edinburgh Project grant
An improved C. elegans model of Alzheimer's disease to monitor neuronal signalling activity Principal Investigator: Dr Jamie Johnston, University of Leeds PhD Studentship
3D bio-printing human pluripotent stem cell-derived skeletal muscle constructs for disease modelling and drug discovery Principal Investigator: Dr Yung-Yao Lin, Queen Mary University of London PhD Studentship
Development of non-mammalian, preclinical screening tools for the predictive analysis of cardiotoxicity Principal Investigator: Dr Grant Wheeler, University of East Anglia PhD Studentship
Developing an in silico, spectroscopic imaging toolkit for assessing skin penetration Principal Investigator: Dr Tao Chen, University of Surrey PhD Studentship
A 3Rs approach to assess drug toxicity on the mammalian embryo during early pregnancy in vitro Principal Investigator: Dr David Turner, University of Liverpool PhD Studentship
Ex vivo drug screening using human tissue to personalise cancer therapy and replace murine avatars Principal Investigator: Dr Spencer Collis, University of Sheffield PhD Studentship
A living biobank of post-surgical residual glioblastoma to replace animal studies Principal Investigator: Dr Spencer Collis, University of Sheffield PhD Studentship
Development of an in vitro model to dissect the mechanism of fungal persistence in the cystic fibrosis lung Principal Investigator: Professor Paul Bowyer, University of Manchester PhD Studentship
Use of induced pluripotent stem cell derived cardiomyocytes to test the consequences of genetic variants in atrial and ventricular arrhythmias Principal Investigator: Dr Katja Gehmlich, University of Birmingham PhD Studentship