The welfare benefits of double-decker rodent cages in allowing rats to engage in natural behaviours.
Expectations of the major UK research council and charitable funding bodies for those working with vertebrates in biosciences research.
A video tutorial for technical staff and researchers in how to handle mice using non-aversive methods.
Dr Simon Bate, from Statistical Sciences, GSK, covers a few questions about statistics and the 3Rs that he regularly encounters.
A video overview of common practices in preclinical research, and specific actions that can be taken to improve its robustness.
Discussing key considerations when determining the effect size for a study, including why this is important for sample size calculations.
A recorded talk explaining the dangers of underpowered experiments and how good design can increase the chances of finding reliable results.
A recorded talk highlighting where bias can be introduced into experiments and the implications for results.
Group housed zebrafish show lower levels of stress and anxiety when they undergo procedures than those who are housed singly.
Guidelines on non-human primate accommodation, care and use adopted by the major UK bioscience funders.
Key issues for the humane killing of laboratory animals.
Resources to help researchers access and use human tissue.
A comprehensive resource on common marmosets, funded by the NC3Rs.
It starts at the very beginning: Scientific and welfare reasons for reviewing neonate care
General principles in analgesia to support best practice.
Things to consider when designing your animal experiments.
F0-ols Rush In: Improving reproducibility and avoiding genetic mosaicism using CRISPR/Cas9 technology.
Examples of study designs that may be used for microsampling from either main study animals or from satellite groups of animals.
Watch your Back! The importance of background strain.
A discussion on the possible impact of genetic drift on the integrity of the data from GA mouse studies
A discussion of the animal welfare challenges around the generation of GA mice, and strategies for improving welfare.
Information to help refine the housing and husbandry of laboratory non-human primates.
Guidance on implementing positive reinforcement training methods.
General principles for welfare assessments.