View Nathalie's Office-led projects
Other programmes of work
External roles
- Advisory Board of the Swiss Reproducibility Network
- Steering Board of the Reproducibility by Design programme, University of Bristol
- Scientific Advisory Board member for the DECIDE project, which accompanies BMBF-funded project groups replicating their preclinical findings in multicentrentre confirmatory studies
Previous appointments
- Scientific Advisory Board member of the Swiss 3R Competence Centre
- Associate Editor for BMJ Open Science
NC3Rs publications
The RIVER working group (2023). Reporting In Vitro Experiments Responsibly – the RIVER Recommendations. MetaArXiv Preprints. doi: 10.31222/osf.io/x6aut
Karp NA, Pearl EJ, Stringer EJ, Barkus C, Ulrichsen JC, Percie du Sert N (2022). A qualitative study of the barriers to using blinding in in vivo experiments and suggestions for improvement. PLoS Biol. doi: 10.1371/journal.pbio.3001873
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen O, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Wurbel H (2020). The ARRIVE guidelines 2.0: updated guidelines for reporting animal research. PLoS Biol 18(7): e3000410. doi: 10.1371/journal.pbio.3000410
The ARRIVE guidelines 2.0 are also published in BMC Vet Res, BMJ Open Science, Br J Pharmacol, J Exp Physiol, J Cerebr Blood F Met, J Physiol and Vet Clin Pathol.
Percie du Sert N, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Hurst V, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Wurbel H (2020). Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0. PLoS Biol 18(7): e3000411. doi: 10.1371/journal.pbio.3000411
Koroshetz WJ, Behrman S, Brame CJ, Branchaw JL, Brown EN, Clark EA, Dockterman D, Elm JJ, Gay PL, Green KM, Hsi S, Kaplitt MG, Kolber BJ, Kolodkin AL, Lipscombe D, MacLeod MR, McKinney CC, Munafo MR, Oakley B, Olimpo JT, Percie du Sert N, Raman IM, Riley C, Shelton AL, Uzzo SM, Crawford DC, Silberberg SD (2020). Framework for advancing rigorous research. eLife 9 e55915. doi: 10.7554/eLife.55915
Huang W, Percie du Sert N, Vollert J, Rice ASC (2019). General principles of preclinical study design. Handbook of Experimental Pharmacology epub: 1-15. doi: 10.1007/164_2019_277
Percie du Sert N, Ahluwalia A, Alam S, Avey MT, Baker M, Browne W, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Hurst V, Karp NA, Lidster K, Maccallum CJ, Macleod M, Pearl EJ, Petersen O, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Würbel H (2019). Reporting animal research: Explanation and Elaboration for the ARRIVE guidelines 2019. bioRxiv 703355. doi: 10.1101/703355
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Karp NA, Lidster K, Maccallum CJ, Macleod M, Petersen O, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Würbel H (2019). The ARRIVE guidelines 2019: updated guidelines for reporting animal research. bioRxiv 703181. doi: 10.1101/703181
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Altman DG, Avey MT, Baker M, Browne W, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Howells DW, Karp NA, MacCallum CJ, Macleod M, Petersen O, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Würbel H, Holgate ST (2018). Revision of the ARRIVE guidelines: rationale and scope. BMJ Open Sci 0:e000002. doi: 10.1136/bmjos-2018-000002
Percie du Sert N and Robinson V (2018). The NC3Rs gateway: Accelerating scientific discoveries with new 3Rs models and technologies. F1000Res 7:591. doi: 10.12688/f1000research.14964.1
Percie du Sert N, Bamsey I, Bate ST, Berdoy M, Clark RA, Cuthill IC, Fry D, Karp NA, Macleod M, Moon L, Stanford SC, Lings B (2017). The Experimental Design Assistant. Nat Meth 14: 1024-5 doi: 10.1038/nmeth.4462
Percie du Sert N, Bamsey I, Bate ST, Berdoy M, Clark RA, Cuthill IC, Fry D, Karp NA, Macleod M, Moon L, Stanford SC, Lings B (2017). The Experimental Design Assistant. PLoS Biol 15:e2003779. doi: 10.1371/journal.pbio.2003779
Percie du Sert N, Alfieri A, Allan SM, Carswell HVO, Deuchar GA, Farr TD, Flecknell P, Gallagher L, Gibson CL, Haley MJ, Macleod MR, Mccoll BW, Mccabe C, Morancho A, Moon LDF, O’Neill MJ, Pérez de Puig I, Planas A, Ragan CI, Rosell A, Roy LA, Ryder KO, Simats A, Sena ES, Sutherland BA, Tricklebank MD, Trueman RC, Whitfield L, Wong R, Macrae IM (2017). The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments). J Cereb Blood Flow Metab. doi: 10.1177/0271678X17709185
Munafò MR, Nosek BA, Bishop DVM, Button KS, Chambers CD, Percie du Sert N, Simonsohn, U, Wagenmakers, E-J, Ware, JJ, Ioannidis, JPA (2017). A manifesto for reproducible science. Nat Hum Behav 1: 0021. doi: 10.1038/s41562-016-0021
Percie du Sert N, Rice AS (2014) Improving the translation of analgesic drugs to the clinic: animal models of neuropathic pain. Br J Pharmacol 171(12): 2951-2963. doi: 10.1111/bph.12645
Percie du Sert N, Andrews PL (2014) The Ferret in Nausea and Vomiting Research: Lessons in Translation of Basic Science to the Clinic. In: Biology and Diseases of the Ferret, 3rd edition (Ed. Fox JG, Marini RP) John Wiley & Sons, Inc. doi: 10.1002/9781118782699.ch31
Percie du Sert N (2012). Maximising the output of osteoarthritis research: the ARRIVE guidelines. Osteoarthritis Cartilage 20(4): 253-5. doi: 10.1016/j.joca.2011.12.017
Percie du Sert N, Andrews PL, Holmes AM, Wallis R (2012). Predicting the emetic liability of novel chemical entities: a comparative study. Br J Pharmacol 165(6): 1848-67. doi: 10.1111/j.1476-5381.2011.01669.x
Percie du Sert N (2011). Systematic review and meta-analysis of pre-clinical research: the need for reporting guidelines. Eur Heart J 32(19): 2340. doi: 10.1093/eurheartj/ehr271
Percie du Sert N (2011). Improving the reporting of animal research: when will we ARRIVE? Dis Model Mech 4(3): 281-2. doi: 10.1242/dmm.007971
NC3Rs blogs:
- (2015) Improving the design of animal experiments: Introducing the Experimental Design Assistant (EDA)
For additional publications, see Nathalie's ResearchGate profile.
Qualifications
PhD, Physiology
St George's University of London, 2005-2009
An investigation into the mechanism of cisplatin-induced emesis.
BSc Hons, Biology
Kingston University, London, 2001-2003
DEUG, Life Sciences
Université Claude Bernard Lyon I (France), 1999-2001