Registration Details
Advances in in vitro and in silico approaches are reshaping drug development by improving the prediction of efficacy, safety and pharmacokinetics. This workshop will focus on two priority targets identified in the UK Government’s 2025 alternative methods strategy: reducing reliance on animal studies in pharmacokinetic and cardiovascular safety studies.
Sessions will bring together scientists and stakeholders to discuss the current landscape and identify gaps and opportunities where replacement technologies could improve study outcomes, increase human relevance and minimise animal use. The outputs will help to define how the Government targets can be delivered in practice through supporting research collaboration and innovation.
To support this ambition we are working in partnership with Innovate UK to deliver the 'Industrial human-relevant drug models' competition, with £2M available to accelerate the adoption of non-animal approaches for pharmacokinetic prediction and cardiovascular safety.
Registration
This event is intended for scientists and other professional stakeholders working in related scientific fields. Please register with an institutional email address. Registrations will be reviewed in line with our terms and conditions and policy on attendance at NC3Rs events (PDF).
When registering, please indicate your preferred workshop topic for breakout sessions: cardiovascular safety, pharmacokinetics or no preference.
Agenda
| Time | Session |
|---|---|
| 10.00 – 10.30 | Registration and coffee |
| 10.30 – 10.40 | Welcome address Mike Capaldi, Newcastle University (Chair) |
| 10.40 – 11.00 | The UK Government’s alternatives strategy Anthony Holmes, NC3Rs |
| 11.00 – 11.30 | Innovate UK and Business Connect overview Grace Ford, Innovate UK Jessica Dobson, Innovate Business Connect |
| 11.30 – 12.00 | Industry perspective: Pharmacokinetic studies Gareth Lewis, GSK |
| 12.00 – 12.30 | Industry perspective: Cardiovascular safety studies Carol De Santis, AstraZeneca |
| 12.30 – 13.30 | Lunch |
| 13.30 – 13.40 | Workshop briefing |
13.40 – 15.00 (parallel sessions) | Delegates will work through a series of topics examining the gaps and opportunities for improving the uptake of alternatives to move towards Government targets. Workshop 1 – Cardiovascular safety Workshop 2 – Pharmacokinetics |
| 15.00 – 15.15 | Break |
| 15.15 – 16.00 | Feedback from workshops |
| 16.00 – 16.15 | Discussion and Q&A |
| 16.15 – 17.00 | Networking |